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B1YXF5 (B1YXF5_BURA4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:BamMC406_4561
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP]
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2281 By similarity HAMAP MF_01265
Binding site1321NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1981NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
B1YXF5 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 82F588A092B58644

FASTA27528,635
        10         20         30         40         50         60 
MRNGHAHGHA PVDVAMIGFG AIGAAVYHAV EHDASLRVAH VIVPEHQRDA VQRELGGAVE 

        70         80         90        100        110        120 
VVSSVDALAR RPEFALECAG HSALVDHVVP LLKAGTDCAV ASIGALSDLA LLDVLSQAAD 

       130        140        150        160        170        180 
EGDATLTLLS GAIGGIDALA SARQGGLDEV LYVGRKPPLG WLGTPAEELC DLRAMTEEKV 

       190        200        210        220        230        240 
IFEGTARDAA RLYPKNANVA ATVALAGLGL DATRVRLIAD PAVTRNVHRI TARGAFGEMS 

       250        260        270 
LEMSGKPLPD NPKTSALTAY CAIRALRNRA ARCVI

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References

[1]"Complete sequence of chromosome 2 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001026 Genomic DNA. Translation: ACB67017.1.
RefSeqYP_001811233.1. NC_010552.1.

3D structure databases

ProteinModelPortalB1YXF5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YXF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6179310.
GenomeReviewsGene locus BamMC406_4561 in contig CP001026_GR.
KEGGbac:BamMC406_4561.
PATRIC19038883. VBIBurAmb82852_4730.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1YXF5_BURA4
AccessionPrimary (citable) accession number: B1YXF5
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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