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B1YVJ0

- PNCB_BURA4

UniProt

B1YVJ0 - PNCB_BURA4

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Protein

Nicotinate phosphoribosyltransferase

Gene
pncB, BamMC406_0980
Organism
Burkholderia ambifaria (strain MC40-6)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciBAMB398577:GH38-1013-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:BamMC406_0980
OrganismiBurkholderia ambifaria (strain MC40-6)
Taxonomic identifieri398577 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000001680: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Nicotinate phosphoribosyltransferaseUniRule annotationPRO_1000129463Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi398577.BamMC406_0980.

Structurei

3D structure databases

ProteinModelPortaliB1YVJ0.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

B1YVJ0-1 [UniParc]FASTAAdd to Basket

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MIITSLLDTD LYKFTMMQVV LHHFPAANVE YRFRCRTPGV DLVPYIDEIR    50
DEVRGLCSLR FTDIELDYLR RMRFIKSDFV DFLALFHLNE KYISITPSPK 100
GNGEIDIVIE GPWLHTILFE IPVLAIVNEV YFRNTQREPD YREGRERLRE 150
KIKLLGAKPE FADCKIADYG TRRRFSKVWH EEVALTLRDG LGPQFAGTSN 200
VFYAMKHELT PLGTMAHEYL QACQALGPRL RDSQTYGFEM WAKEYRGDLG 250
IALSDVYGMD AFLNDFDMYF CKLFDGARHD SGDPFEWGER MLRHYEANRC 300
DPRTKVLVFS DALDIPKVMQ LYERFRNRCK LAFGVGTNLT NDLGYVPLQI 350
VIKMVRCNGQ PVAKLSDSPG KSMCDDRAYL AYLRQVFGIA QPVDDDASQ 399
Length:399
Mass (Da):46,153
Last modified:May 20, 2008 - v1
Checksum:iCE3918E088C9A9C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001025 Genomic DNA. Translation: ACB63471.1.
RefSeqiWP_012363386.1. NC_010551.1.
YP_001807687.1. NC_010551.1.

Genome annotation databases

EnsemblBacteriaiACB63471; ACB63471; BamMC406_0980.
GeneIDi6178837.
KEGGibac:BamMC406_0980.
PATRICi19031320. VBIBurAmb82852_0998.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001025 Genomic DNA. Translation: ACB63471.1 .
RefSeqi WP_012363386.1. NC_010551.1.
YP_001807687.1. NC_010551.1.

3D structure databases

ProteinModelPortali B1YVJ0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 398577.BamMC406_0980.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB63471 ; ACB63471 ; BamMC406_0980 .
GeneIDi 6178837.
KEGGi bac:BamMC406_0980.
PATRICi 19031320. VBIBurAmb82852_0998.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci BAMB398577:GH38-1013-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6."
    Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.
    , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC40-6.

Entry informationi

Entry nameiPNCB_BURA4
AccessioniPrimary (citable) accession number: B1YVJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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