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B1YV33 (AROA_BURA4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:BamMC406_0925
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP]
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4344343-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099669

Sequences

Sequence LengthMass (Da)Tools
B1YV33 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 805D4214034477D2

FASTA43446,337
        10         20         30         40         50         60 
MDYLDLGPYS SASGTVRLPG SKSISNRVLL LAALAEGDTT ITNLLDSDDT RVMLDALGKL 

        70         80         90        100        110        120 
GVKLARDGDT CVVTGTRGAF TAKTADLFLG NAGTAVRPLT AALAINGGDY RVHGVPRMHE 

       130        140        150        160        170        180 
RPIGDLVDGL RQIGAQIDYE QNEGFPPLRI KPGTISVDAP IRVRGDVSSQ FLTALLMTLP 

       190        200        210        220        230        240 
LVKAKDGRTV VEIDGELISK PYIDITIRLM ERFGVTVERD GWQRFVAPAG VRYRSPGRIM 

       250        260        270        280        290        300 
VEGDASSASY FLAAGALGGG PLRVEGVGRA SIQGDVGFAN ALMQMGANVS MGDDWIEVRG 

       310        320        330        340        350        360 
IGHDHGKLDP IDMDFNLIPD AAMTIAVAAL FASGTSTLRN IASWRVKETD RIAAMATELR 

       370        380        390        400        410        420 
KVGAIVEEGA DYLVVTPPQR LTPNAAIDTY DDHRMAMCFS LVSLGGVPVR INDPKCVGKT 

       430 
FPDYFDRFAA LAKA

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC40-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001025 Genomic DNA. Translation: ACB63416.1.
RefSeqYP_001807632.1. NC_010551.1.

3D structure databases

ProteinModelPortalB1YV33.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YV33.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6178901.
GenomeReviewsGene locus BamMC406_0925 in contig CP001025_GR.
KEGGbac:BamMC406_0925.
PATRIC19031203. VBIBurAmb82852_0942.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAGADIEWG.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycBAMB398577:BAMMC406_0925-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BURA4
AccessionPrimary (citable) accession number: B1YV33
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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