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B1YUZ7 (F16PA_BURA4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name:fbp
Ordered Locus Names:BamMC406_0889
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP]
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 339339Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364485

Regions

Region119 – 1224Substrate binding By similarity

Sites

Metal binding941Magnesium 1 By similarity
Metal binding1161Magnesium 1 By similarity
Metal binding1161Magnesium 2 By similarity
Metal binding1181Magnesium 1; via carbonyl oxygen By similarity
Metal binding1191Magnesium 2 By similarity
Metal binding2821Magnesium 2 By similarity
Binding site2101Substrate By similarity
Binding site2761Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
B1YUZ7 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: C3200A2E65EB7AD4

FASTA33937,313
        10         20         30         40         50         60 
MSIARRTTLS KFLIEQQRET NNLPADLRLL IEVVARACKA ISYNVSKGAL GEALGTAGSE 

        70         80         90        100        110        120 
NVQGEVQKKL DILSNEILLD ANEWGGNLAA MASEEMETFF PIPANYPRGE YLLVFDPLDG 

       130        140        150        160        170        180 
SSNIDVNVSI GTIFSVLRCP DGKQATEESF LQPGTEQVAA GYAVYGPQTV FVLTTGNGVN 

       190        200        210        220        230        240 
CFTLDREVGS WVLTQSNMQI PADTREYAIN ASNARHWYEP VQRYVDELNA GKDGPRGDNF 

       250        260        270        280        290        300 
NMRWIASMVA DVHRILNRGG IFMYPADKRT PDRPGKLRLM YEANPMSFIV EQAGGAATTG 

       310        320        330 
TQRIMEVQPT GLHQRVPVFL GSKNEVERVT SYHAEGEGK

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References

[1]"Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC40-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001025 Genomic DNA. Translation: ACB63380.1.
RefSeqYP_001807596.1. NC_010551.1.

3D structure databases

ProteinModelPortalB1YUZ7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YUZ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6178438.
GenomeReviewsGene locus BamMC406_0889 in contig CP001025_GR.
KEGGbac:BamMC406_0889.
PATRIC19031133. VBIBurAmb82852_0907.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMAHWEAPVQ.
ProtClustDBPRK09293.

Enzyme and pathway databases

BioCycBAMB398577:BAMMC406_0889-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16PA_BURA4
AccessionPrimary (citable) accession number: B1YUZ7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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