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B1YU51 (B1YU51_BURA4) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138
Ordered Locus Names:BamMC406_2212 EMBL ACB64691.1
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP] EMBL ACB64691.1
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex ›

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain107 – 314208ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding133 – 19462ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2841Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2861Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
B1YU51 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 7C5DE2C9643362B9

FASTA42645,607
        10         20         30         40         50         60 
MKLLVVGSGG REHALAWKLA QSPRVQMVYV APGNGGTAQD ERLKNVDITS LDALADFAES 

        70         80         90        100        110        120 
EGVAFTLVGP EAPLAAGIVN LFRARGLKVF GPTREAAQLE SSKDFAKAFM KRHGIPTADY 

       130        140        150        160        170        180 
ETFSDAAAAH AYIDTKGAPI VVKADGLAAG KGVVVAMTLE EAHAAVDMML SGNKLGDAGA 

       190        200        210        220        230        240 
RVVIEEFLDG EEASFIVMVD GKHALALASS QDHKRLLDED RGPNTGGMGA YSPAPIVTPQ 

       250        260        270        280        290        300 
MHARVMREII MPTVRGMEKD GIRFTGFLYA GLMIDKEGNP RTLEFNCRMG DPETQPIMAR 

       310        320        330        340        350        360 
LKSDFSKVVE QAIAGTLDSV ELDWDRRTAL GVVLAAHGYP DAPRKGDRIN GIPAETAQAV 

       370        380        390        400        410        420 
TFHAGTTLAE GDKLVTSGGR VLCVVGLADS VREAQQHAYD TINQINFEGM QYRRDIGFRA 


LNRKSA

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC40-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001025 Genomic DNA. Translation: ACB64691.1.
RefSeqYP_001808907.1. NC_010551.1.

3D structure databases

ProteinModelPortalB1YU51.
SMRB1YU51. Positions 1-423.
ModBaseSearch...

Protein-protein interaction databases

STRING398577.BamMC406_2212.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB64691; ACB64691; BamMC406_2212.
GeneID6177916.
KEGGbac:BamMC406_2212.
PATRIC19033933. VBIBurAmb82852_2268.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0151.
HOGENOMHOG000033463.
KOK01945.
OMAMGAYTPL.
ProtClustDBPRK00885.

Enzyme and pathway databases

BioCycBAMB398577:GH38-5988-MONOMER.
UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1YU51_BURA4
AccessionPrimary (citable) accession number: B1YU51
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info