B1YRC7 (B1YRC7_BURA4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor G 1 HAMAP MF_00054
Short name=EF-G 1 HAMAP MF_00054

Gene names

Name:	fusA1 HAMAP MF_00054
Ordered Locus Names:	BamMC406_0273

Organism

Burkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP] EMBL ACB62774.1

Taxonomic identifier

398577 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	700 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome By similarity. HAMAP MF_00054
Subcellular location	Cytoplasm By similarity HAMAP MF_00054.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. HAMAP MF_00054

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP MF_00054
Ligand	GTP-binding RuleBase RU000323 HAMAP MF_00054 Nucleotide-binding
Molecular function	Elongation factor HAMAP MF_00054 EMBL ACB62774.1
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	17 – 24	8	GTP By similarity HAMAP MF_00054
	Nucleotide binding	88 – 92	5	GTP By similarity HAMAP MF_00054
	Nucleotide binding	142 – 145	4	GTP By similarity HAMAP MF_00054

Sequences

	Sequence		Length	Mass (Da)
	B1YRC7 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 49F09F6F8AE39F4D	FASTA	700	77,507
	10 20 30 40 50 60 MARKTPIERY RNIGISAHID AGKTTTTERI LFYTGVNHKI GEVHDGAATM DWMEQEQERG 70 80 90 100 110 120 ITITSAATTA FWKGMGGNYP EHRINIIDTP GHVDFTIEVE RSMRVLDGAC MVYCAVGGVQ 130 140 150 160 170 180 PQSETVWRQA NKYKVPRLAF VNKMDRTGAN FFKVYDQLRL RLKANPVPVV VPIGSEENFK 190 200 210 220 230 240 GVVDLIKMKA IIWDEASQGT KFDYVDIPAE LAETCKEWRE KMVEVAAEAN EDLMNKYLEE 250 260 270 280 290 300 GDLPEADIVK ALRDRTIACE IQPMLCGTAF KNKGVQRMLD AVIDFLPSPV DIPPVKGELE 310 320 330 340 350 360 NGEAAERKAS DDEKFSSLAF KIMTDPFVGQ LIFFRVYSGV VNSGDTLLNS TKGKKERLGR 370 380 390 400 410 420 ILQMHANQRE EIKEVRAGDI AAAVGLKEAT TGDTLCDPAN PIVLERMVFP EPVISQAVEP 430 440 450 460 470 480 KTKADQEKMG LALNRLAQED PSFRVQTDEE SGQTIISGMG ELHLEILVDR MKREFGVEAT 490 500 510 520 530 540 VGKPQVAYRE TIRSTAKDVD GKFVKQSGGR GQYGHAVITL EPNEQGKGYE FFDEIKGGVI 550 560 570 580 590 600 PREYIPAVDK GIQDTLKSGV LAGFPVVDVK VHLTFGSYHD VDSNENAFRM AGSMAFKEAM 610 620 630 640 650 660 RKANPVVLEP MMAVEVETPE DYMGNVMGDL SGRRGIVQGM EDMVGGGKIV RAEVPLSEMF 670 680 690 700 GYSTSLRSLT QGRATYTMEF KHYAEAPRNV AEAIISAKSK

References

[1]

"Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. , Ramette A., Konstantinidis K., Tiedje J., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001025 Genomic DNA. Translation: ACB62774.1.
RefSeq	YP_001806990.1. NC_010551.1.
3D structure databases
ProteinModelPortal	B1YRC7.
SMR	B1YRC7. Positions 1-695.
ModBase	Search...
Protein-protein interaction databases
STRING	B1YRC7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6176364.
GenomeReviews	Gene locus BamMC406_0273 in contig CP001025_GR.
KEGG	bac:BamMC406_0273.
PATRIC	19029839. VBIBurAmb82852_0277.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG737692.
OMA	CNEWREK.
ProtClustDB	PRK00007.
Family and domain databases
HAMAP	MF_00054_B. EF_G_EF_2_B. [Tree]
InterPro	IPR009022. Elongation_fac_G/III/V. IPR000795. ProtSyn_GTP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR005225. Small_GTP-bd_dom. IPR004540. Transl_elong_EFG/EF2. IPR000640. Transl_elong_EFG/EF2_C. IPR005517. Transl_elong_EFG/EF2_IV. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.30.70.240. Transl_elong_EFG/EF2_C. 1 hit.
KO	K02355.
Pfam	PF00679. EFG_C. 1 hit. PF03764. EFG_IV. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SMART	SM00838. EFG_C. 1 hit. SM00889. EFG_IV. 1 hit. [Graphical view]
SUPFAM	SSF54980. EFG_III_V. 2 hits. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00484. EF-G. 1 hit. TIGR00231. Small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1YRC7_BURA4

Accession

Primary (citable) accession number: B1YRC7

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)