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B1YMV6 (B1YMV6_BURA4) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Carbamoyl-phosphate synthase small chain HAMAP-Rule MF_01209
EC=6.3.5.5 HAMAP-Rule MF_01209
Alternative name(s):
Carbamoyl-phosphate synthetase glutamine chain HAMAP-Rule MF_01209
Gene names
Name:carA HAMAP-Rule MF_01209
Ordered Locus Names:BamMC406_1179 EMBL ACB63670.1
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP] EMBL ACB63670.1
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex ›

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate. HAMAP-Rule MF_01209

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1. HAMAP-Rule MF_01209

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3. HAMAP-Rule MF_01209 SAAS SAAS006274

Subunit structure

Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate By similarity. HAMAP-Rule MF_01209

Sequence similarities

Belongs to the CarA family. HAMAP-Rule MF_01209

Contains 1 glutamine amidotransferase type-1 domain. HAMAP-Rule MF_01209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain192 – 379188Glutamine amidotransferase type-1 By similarity HAMAP-Rule MF_01209
Region1 – 188188CPSase By similarity HAMAP-Rule MF_01209

Sites

Active site2681Nucleophile By similarity HAMAP-Rule MF_01209
Active site3521 By similarity HAMAP-Rule MF_01209
Active site3541 By similarity HAMAP-Rule MF_01209

Sequences

Sequence LengthMass (Da)Tools
B1YMV6 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 813B78F266FF5652

FASTA38140,904
        10         20         30         40         50         60 
MLPSFSPALL ALADGTVFRG YSIGAEGHTI GEVVFNTAIT GYQEILTDPS YARQIVTLTY 

        70         80         90        100        110        120 
PHIGNVGINA EDVEATKVHA AGLIIRDLPT LASNFRMDRT LGDYLRDEGV VAIAGIDTRK 

       130        140        150        160        170        180 
LTRILRDKGA QNGCILAGSD DEAKAIELAR SFPGLAGMDL AKVVSTTKPF EWKQTEWRLE 

       190        200        210        220        230        240 
GGYGMQESPK YRVVAYDFGV KYNILRMLAE RGCQVTVLPA QASAADALAL NPDGIFLSNG 

       250        260        270        280        290        300 
PGDPEPCDYA IAATKEFIER GVPTFGICLG HQIMGLAVGA KTLKMKTGHH GANHPVKDLG 

       310        320        330        340        350        360 
DGRVVITSQN HGFAVDADSL PANARVTHVS LFDGTLQGFE LTDKPAFCFQ GHPEASPGPH 

       370        380 
DIGYLFDRFT ALMDAAQQRN A

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References

[1]"Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC40-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001025 Genomic DNA. Translation: ACB63670.1.
RefSeqYP_001807886.1. NC_010551.1.

3D structure databases

ProteinModelPortalB1YMV6.
SMRB1YMV6. Positions 8-374.
ModBaseSearch...

Protein-protein interaction databases

STRING398577.BamMC406_1179.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB63670; ACB63670; BamMC406_1179.
GeneID6178842.
KEGGbac:BamMC406_1179.
PATRIC19031756. VBIBurAmb82852_1211.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0505.
HOGENOMHOG000038087.
KOK01956.
OMARDSHYLF.
ProtClustDBPRK12564.

Enzyme and pathway databases

BioCycBAMB398577:GH38-4926-MONOMER.
UniPathwayUPA00068; UER00171.
UPA00070; UER00115.

Family and domain databases

Gene3D3.50.30.20. 1 hit.
HAMAPMF_01209. CPSase_S_chain.
InterProIPR006274. CarbamoylP_synth_ssu.
IPR002474. CarbamoylP_synth_ssu_N.
IPR017926. GATASE_1.
[Graphical view]
PfamPF00988. CPSase_sm_chain. 1 hit.
PF00117. GATase. 1 hit.
[Graphical view]
SMARTSM01097. CPSase_sm_chain. 1 hit.
[Graphical view]
SUPFAMSSF52021. CP_synthsmall. 1 hit.
TIGRFAMsTIGR01368. CPSaseIIsmall. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1YMV6_BURA4
AccessionPrimary (citable) accession number: B1YMV6
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info