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B1YKW2 (FENR1_EXIS2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase 1
Short name=FNR 1
Short name=Fd-NADP+ reductase 1
EC=1.18.1.2
Gene names
Ordered Locus Names:Exig_2313
OrganismExiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) [Complete proteome] [HAMAP]
Taxonomic identifier262543 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331Ferredoxin--NADP reductase 1 HAMAP MF_01685
PRO_0000364834

Sites

Binding site341FAD By similarity
Binding site421FAD By similarity
Binding site471FAD By similarity
Binding site871FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1211FAD; via amide nitrogen By similarity
Binding site2821FAD By similarity
Binding site3221FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
B1YKW2 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: C6248BF16D29F282

FASTA33136,622
        10         20         30         40         50         60 
MHQPYDVTII GGGPVGLFTA FYSGMRQMKT KVIESLPQLG GQLATLYPEK YIYDIAGFPK 

        70         80         90        100        110        120 
VKAQDLVDRL LEQANEFDPT YVLGETVLAY ERLDDGLIRL VTNKGEHYTK TVILTAGNGS 

       130        140        150        160        170        180 
FAARPLGVAD AERFEGSNLH YFVNEMDRFK DRQVVLLGGG DSAVDWSLML EPIAKSVTLV 

       190        200        210        220        230        240 
HRRDKFRAHE HTVELLHNSS VNVMTPYTLE SVTGEDSIET LTFKHAETDE VIVVGADDVV 

       250        260        270        280        290        300 
CNFGFVSSLG PLKEWEVEFE RNSIRVNSKM ETAIPGVFAC GDIATYDGRV KLIATGFGEA 

       310        320        330 
PIAVNQAKLL VDPSARHPQH STSLFEKVKN H

« Hide

References

[1]"Complete sequence of chromosome of Exiguobacterium sibiricum 255-15."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T., Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17290 / JCM 13490 / 255-15.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001022 Genomic DNA. Translation: ACB61764.1.
RefSeqYP_001814781.1. NC_010556.1.

3D structure databases

ProteinModelPortalB1YKW2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YKW2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6174523.
GenomeReviewsGene locus Exig_2313 in contig CP001022_GR.
KEGGesi:Exig_2313.
PATRIC32138258. VBIExiSib53410_2351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMASESAMAC.
ProtClustDBCLSK2489773.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR1_EXIS2
AccessionPrimary (citable) accession number: B1YKW2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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