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B1YKJ8 (B1YKJ8_EXIS2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Exig_0700
OrganismExiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) [Complete proteome] [HAMAP]
Taxonomic identifier262543 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1801Iron By similarity HAMAP MF_00323
Metal binding2611Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B1YKJ8 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 4FDFBB4ACC90832B

FASTA31034,788
        10         20         30         40         50         60 
MKTLGLLVMA YGTPYKPEDI ERYYTHIRRG RKPSPEALAE LTERYEAIGG VSPLAQVTID 

        70         80         90        100        110        120 
QAEELHRQLT EKYAGEIEFK LYLGLKHIEP FVEDAVEQMA KDGITEAVTV VLAPHYSTFS 

       130        140        150        160        170        180 
IRSYNGRAKE VADKHGIHLA SVESWYKEEA FIDWWGTEIR KTFDALPVPE DRAVLVVSAH 

       190        200        210        220        230        240 
SLPEKIIANG DPYPEQLKET ADLIAARAGV KHMITGWQSA GQTPEPWLGP DVQDLTRDVY 

       250        260        270        280        290        300 
EAEGYEAFVY VPVGFVADHL EVLFDNDYEC KVVCDELGIH YARPIMPNAD PAFMKAVTEA 

       310 
VSKQVGSYVK

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References

[1]"Complete sequence of chromosome of Exiguobacterium sibiricum 255-15."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T., Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17290 / JCM 13490 / 255-15.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001022 Genomic DNA. Translation: ACB60181.1.
RefSeqYP_001813198.1. NC_010556.1.

3D structure databases

ProteinModelPortalB1YKJ8.
SMRB1YKJ8. Positions 2-306.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YKJ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6173767.
GenomeReviewsGene locus Exig_0700 in contig CP001022_GR.
KEGGesi:Exig_0700.
PATRIC32134973. VBIExiSib53410_0714.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMACSETIFE.
ProtClustDBPRK12435.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1YKJ8_EXIS2
AccessionPrimary (citable) accession number: B1YKJ8
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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