B1YK21 (B1YK21_EXIS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Ordered Locus Names:

Exig_0621

Organism

Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) [Complete proteome] [HAMAP]

Taxonomic identifier

262543 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL ACB60102.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1YK21 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: CD45D13877C686F9	FASTA	249	27,275
	10 20 30 40 50 60 MMLDYDYDAL REIGRIVAIA RDEMADAVKP GITTKELDEI GARILKEHEA ESAPIVMYDF 70 80 90 100 110 120 PGATCISVNE VAAHGIPGAY VIKEGDIVNV DVSAVKNGYY SDTGKTVIAG QARRPEDVRL 130 140 150 160 170 180 VEVSLSALEK GLEKVKAGTK VNQIGKAIYA ETRKSGFTVI RNLAGHGLGK TLHGEPESIS 190 200 210 220 230 240 NYFSREENDL LKEGQVIAVE TFISTGDEFC MEDEKDGWTL YTPNKSLVSQ FEHSVIVLKD GYEILTKVD

References

[1]

"Complete sequence of chromosome of Exiguobacterium sibiricum 255-15." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T., Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 17290 / JCM 13490 / 255-15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001022 Genomic DNA. Translation: ACB60102.1.
RefSeq	YP_001813119.1. NC_010556.1.
3D structure databases
ProteinModelPortal	B1YK21.
ModBase	Search...
Protein-protein interaction databases
STRING	B1YK21.
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6173429.
GenomeReviews	Gene locus Exig_0621 in contig CP001022_GR.
KEGG	esi:Exig_0621.
PATRIC	32134779. VBIExiSib53410_0635.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299384.
OMA	VFTVEPF.
ProtClustDB	CLSK2489045.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1YK21_EXIS2

Accession

Primary (citable) accession number: B1YK21

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)