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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei139 – 1391GTPUniRule annotation
Binding sitei143 – 1431GTPUniRule annotation
Binding sitei187 – 1871GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 255GTPUniRule annotation
Nucleotide bindingi108 – 1103GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciESIB262543:GHBP-2036-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Exig_1958Imported
OrganismiExiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)Imported
Taxonomic identifieri262543 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
Proteomesi
  • UP000001681 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi262543.Exig_1958.

Structurei

3D structure databases

ProteinModelPortaliB1YIT4.
SMRiB1YIT4. Positions 12-315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 205193TubulinInterPro annotationAdd
BLAST
Domaini207 – 323117Tubulin_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1YIT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHFDEMMDQ VAKIKVIGVG GGGSNAVNRM IEHGVQGVEF IAVNTDAQAL
60 70 80 90 100
NMSQADVKLQ LGAKLTRGLG AGANPEIGKK AAEESREQLT EILSGADMVF
110 120 130 140 150
VTAGMGGGTG TGAAPVIAEI SKEIGALTVG VVTKPFMFEG RKRMQHAVSG
160 170 180 190 200
VQNFKEKVDT LIVIPNDKLL EIVDRNTPML EAFKEADNVL RQGVQGITDL
210 220 230 240 250
IAVPGLINLD FADVKTIMTE KGSALMGVGV ATGEHRATEA AKKAISSPLL
260 270 280 290 300
ETSIEGAKGV LMNITGSANL SLYEVTEAAQ IVQSAADEEV NLIFGSVIND
310 320 330 340 350
NLEDEIIVTV IATEFENEPL DFEIPSAQEM MKNLLKKKQA STPSPVAEEP
360 370 380
KPQVEETPIS SNQESAKGSD VEETMDIPSF LRRNNR
Length:386
Mass (Da):41,086
Last modified:May 20, 2008 - v1
Checksum:i7EA9C7033F9D4BA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001022 Genomic DNA. Translation: ACB61410.1.
RefSeqiWP_012370828.1. NC_010556.1.

Genome annotation databases

EnsemblBacteriaiACB61410; ACB61410; Exig_1958.
KEGGiesi:Exig_1958.
PATRICi32137536. VBIExiSib53410_1991.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001022 Genomic DNA. Translation: ACB61410.1.
RefSeqiWP_012370828.1. NC_010556.1.

3D structure databases

ProteinModelPortaliB1YIT4.
SMRiB1YIT4. Positions 12-315.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262543.Exig_1958.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB61410; ACB61410; Exig_1958.
KEGGiesi:Exig_1958.
PATRICi32137536. VBIExiSib53410_1991.

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Enzyme and pathway databases

BioCyciESIB262543:GHBP-2036-MONOMER.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17290 / JCM 13490 / 255-15Imported.

Entry informationi

Entry nameiB1YIT4_EXIS2
AccessioniPrimary (citable) accession number: B1YIT4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: July 6, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.