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B1YG43 (HTPG_EXIS2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein HtpG
Alternative name(s):
Heat shock protein HtpG
High temperature protein G
Gene names
Name:htpG
Ordered Locus Names:Exig_2981
OrganismExiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) [Complete proteome] [HAMAP]
Taxonomic identifier262543 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium

Protein attributes

Sequence length621 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Molecular chaperone. Has ATPase activity By similarity. HAMAP-Rule MF_00505

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00505

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00505.

Sequence similarities

Belongs to the heat shock protein 90 family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 621621Chaperone protein HtpG HAMAP-Rule MF_00505
PRO_1000127028

Regions

Region1 – 340340A; substrate-binding By similarity
Region341 – 547207B By similarity
Region548 – 62174C By similarity

Sequences

Sequence LengthMass (Da)Tools
B1YG43 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 6CF94EFA96023300

FASTA62171,609
        10         20         30         40         50         60 
METKQFKAES KRLLEMMIHS IYTHKEIFLR ELISNASDAM DKIYYKALTD ETITFDKDAY 

        70         80         90        100        110        120 
KITIEPNKET RQLILRDTGI GMTKDELEEN LGTIAKSGSL AFKAENESKD GHDIIGQFGV 

       130        140        150        160        170        180 
GFYSAFMVAD TVTVVTKPFG SDVAYKWESH GVDGYTIEEV EKEMVGTDIT LHIKANEEDE 

       190        200        210        220        230        240 
NYDEYLEPYR LRSIIKKYSD FIRYPIEMEE TEQRPVEGSD ETESVTVMKT VNSMVPIWRK 

       250        260        270        280        290        300 
NKRELTDEDY RNFYQEKRYG FDAPIKHIHI SADGAVRYQS ILFIPEQPSF DYYSKEFEKG 

       310        320        330        340        350        360 
LELYANGVLI MEKCSDLLPD HFSFVKGMVD SEDLSLNISR EMLQHDRQLK LIAKNIQSKI 

       370        380        390        400        410        420 
KTQLEALLRD DREKYETFYQ AFGRQLKFGI YNDYGMQKDT VKDLVLFHSA KEKKLVTLAE 

       430        440        450        460        470        480 
YVAAMPEEQK YIYYASGEST DRLDKLPQSE LVKDKGFDIL YFTEEIDEFA IQMLLNYDGK 

       490        500        510        520        530        540 
EFKSVTSSDL GIEQTEQAET TETQAEMFKA MQEVLAGHVK EVKASTRLKS HPVCFATDGA 

       550        560        570        580        590        600 
VSIEMEKILK AMPNNQDVAA VKILELNTSH DVFRAIETAY AEDRPKFERY TKLMYQQALL 

       610        620 
MEGLPIEDPV AFANEVCALM I 

« Hide

References

[1]"Complete sequence of chromosome of Exiguobacterium sibiricum 255-15."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T., Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17290 / JCM 13490 / 255-15.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001022 Genomic DNA. Translation: ACB62427.1.
RefSeqYP_001815444.1. NC_010556.1.

3D structure databases

ProteinModelPortalB1YG43.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262543.Exig_2981.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB62427; ACB62427; Exig_2981.
GeneID6175186.
KEGGesi:Exig_2981.
PATRIC32139638. VBIExiSib53410_3024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0326.
HOGENOMHOG000031989.
KOK04079.
OMALTDSPAC.
OrthoDBEOG65TRNM.
ProtClustDBPRK05218.

Enzyme and pathway databases

BioCycESIB262543:GHBP-3079-MONOMER.

Family and domain databases

Gene3D3.30.565.10. 1 hit.
HAMAPMF_00505. HSP90.
InterProIPR003594. HATPase_ATP-bd.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR027058. HtpG.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF28. PTHR11528:SF28. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFPIRSF002583. Hsp90. 1 hit.
PRINTSPR00775. HEATSHOCK90.
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHTPG_EXIS2
AccessionPrimary (citable) accession number: B1YG43
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families