B1YFJ0 (B1YFJ0_EXIS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

Exig_2869

Organism

Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) [Complete proteome] [HAMAP]

Taxonomic identifier

262543 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL ACB62315.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1YFJ0 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: DF1DF12DA98D5826	FASTA	374	39,672
	10 20 30 40 50 60 MIIGVLKEIK NNENRVALTP AGVAALMGQG HTVIVETTAG MGSGFTNEEY TQAGAQIIET 70 80 90 100 110 120 AAEVWATAEL ALKVKEPVAS EYQYFRPELT LFTYLHLAAE PELTRALVDS KITAIAYETV 130 140 150 160 170 180 EKNRTLPLLT PMSEVAGRMA SQIGAQFLEK PHGGMGILLA GVPGVRRGKV TVIGGGVVGT 190 200 210 220 230 240 NAAKLAVGLG ADVTIIDVSP ERLRQLDDIF GNSINTLISN PYTIAEAVAE SDLVVGAVLI 250 260 270 280 290 300 PGAKAPKLVT AEMVERMKPG SVIVDVAIDQ GGIFETVDRI STHDDPTYEK FGVVHYAVAN 310 320 330 340 350 360 MPGAVPRTST LALTNATLPY VLELANKGTH RALAENAALE KGLNVVQGFV TYEAVARDLG 370 YTYKSVEDVL HLHA

References

[1]

"Complete sequence of chromosome of Exiguobacterium sibiricum 255-15." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T., Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 17290 / JCM 13490 / 255-15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001022 Genomic DNA. Translation: ACB62315.1.
RefSeq	YP_001815332.1. NC_010556.1.
3D structure databases
ProteinModelPortal	B1YFJ0.
SMR	B1YFJ0. Positions 1-357.
ModBase	Search...
Protein-protein interaction databases
STRING	B1YFJ0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6173334.
GenomeReviews	Gene locus Exig_2869 in contig CP001022_GR.
KEGG	esi:Exig_2869.
PATRIC	32139414. VBIExiSib53410_2912.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289735.
OMA	RGHEVII.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1YFJ0_EXIS2

Accession

Primary (citable) accession number: B1YFJ0

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)