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B1YD56 (AROC_THENV) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Tneu_0780
OrganismThermoproteus neutrophilus (strain DSM 2338 / JCM 9278 / V24Sta) [Complete proteome] [HAMAP]
Taxonomic identifier444157 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Thermoproteus

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Chorismate synthase HAMAP MF_00300
PRO_1000115410

Sequences

Sequence LengthMass (Da)Tools
B1YD56 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 66B6130788F7A56F

FASTA36539,486
        10         20         30         40         50         60 
MNTFGRELRI TTFGESHGKA IGVVIDGVPA GLELTEEDIK RELERRMFCH IPVLNPRCEP 

        70         80         90        100        110        120 
EEVEILSGVK EGYTQGTPIA VVIWNRRVIS SYYEELWMKP RPGHADFAYY LKYGRHYDHR 

       130        140        150        160        170        180 
GGGRASGRTT AAVVAAGAVA KKMLALAGAE VAGHIVELGG VEINASYTYE DVKKSWGRPL 

       190        200        210        220        230        240 
PVVDQQALDK MLEKIREAAM RGDSIGGGVE VWAVGVPPGL GEPHFGKIKA DIAAAAFSIP 

       250        260        270        280        290        300 
GAIALDWGMG RALAKMWGSE ANDPITVANG RPTLATNKIG GVLGGITVGT PIYFRAWFKP 

       310        320        330        340        350        360 
TPSVRKPQQT VDLAKMEPTT IEFKGRYDVS IVPKALVALE AITAVALADH LLRAGLIRRD 


KPLGR

« Hide

References

[1]"Complete sequence of Thermoproteus neutrophilus V24Sta."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M., Saltikov C., House C.H., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2338 / JCM 9278 / V24Sta.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001014 Genomic DNA. Translation: ACB39719.1.
RefSeqYP_001794165.1. NC_010525.1.

3D structure databases

ProteinModelPortalB1YD56.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1YD56.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6164324.
GenomeReviewsGene locus Tneu_0780 in contig CP001014_GR.
KEGGtne:Tneu_0780.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_THENV
AccessionPrimary (citable) accession number: B1YD56
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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