Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA (guanine(26)-N(2))-dimethyltransferase

Gene

trm1

Organism
Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.UniRule annotation

Catalytic activityi

2 S-adenosyl-L-methionine + guanine(26) in tRNA = 2 S-adenosyl-L-homocysteine + N(2)-dimethylguanine(26) in tRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding, S-adenosyl-L-methionine, tRNA-binding

Enzyme and pathway databases

BioCyciTNEU444157:GHL2-689-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine(26)-N(2))-dimethyltransferaseUniRule annotation (EC:2.1.1.216UniRule annotation)
Alternative name(s):
tRNA 2,2-dimethylguanosine-26 methyltransferaseUniRule annotation
tRNA(guanine-26,N(2)-N(2)) methyltransferaseUniRule annotation
tRNA(m(2,2)G26)dimethyltransferaseUniRule annotation
Gene namesi
Name:trm1UniRule annotation
Ordered Locus Names:Tneu_0683
OrganismiPyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)
Taxonomic identifieri444157 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000001694 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351tRNA (guanine(26)-N(2))-dimethyltransferasePRO_1000114983Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi444157.Tneu_0683.

Structurei

3D structure databases

ProteinModelPortaliB1YCV9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 350347Trm1 methyltransferaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.UniRule annotation
Contains 1 Trm1 methyltransferase domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01219. Archaea.
COG1867. LUCA.
HOGENOMiHOG000229931.
KOiK00555.
OMAiGRYPRKC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00290. tRNA_dimethyltr_TRM1. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR002905. Trm1.
IPR022923. TRM1_arc_bac.
[Graphical view]
PANTHERiPTHR10631. PTHR10631. 1 hit.
PfamiPF02005. TRM. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51626. SAM_MT_TRM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1YCV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLVLRREGA VQFYAPDPQR YGSIYSAPVF YNPAMEKNRT LSVLLLRTLG
60 70 80 90 100
GGLTVCEPLS GTGVRGIRYA VESKAVARLV LNDISRDAAE LIKKNLELNG
110 120 130 140 150
VDGEVYNDDA NVLLHRLKNV CDVVDIDPFG SPAPYIHAAF RALRDEGLLC
160 170 180 190 200
ATATDTAVLV GRYPRKCLRR YWSTVRKTPF YIELGLRNLV GFIARVAASE
210 220 230 240 250
DFSIRPLMSY WEGHYFRTCV AVARGARDAD DALQNVGYVV YRRGMRQTTQ
260 270 280 290 300
LPDESSSGPL WLGPLGDPLI MHQMAQHGVY SDFLGVLEQE YSIEAPWHYR
310 320 330 340 350
LPEFAVEGVS PTLAEALDLL RRSGIYATAT HMAKDGFKAD AGYGEVKRAL

F
Length:351
Mass (Da):39,045
Last modified:May 20, 2008 - v1
Checksum:i4669560313B152E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB39622.1.

Genome annotation databases

EnsemblBacteriaiACB39622; ACB39622; Tneu_0683.
KEGGitne:Tneu_0683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB39622.1.

3D structure databases

ProteinModelPortaliB1YCV9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444157.Tneu_0683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB39622; ACB39622; Tneu_0683.
KEGGitne:Tneu_0683.

Phylogenomic databases

eggNOGiarCOG01219. Archaea.
COG1867. LUCA.
HOGENOMiHOG000229931.
KOiK00555.
OMAiGRYPRKC.

Enzyme and pathway databases

BioCyciTNEU444157:GHL2-689-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00290. tRNA_dimethyltr_TRM1. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR002905. Trm1.
IPR022923. TRM1_arc_bac.
[Graphical view]
PANTHERiPTHR10631. PTHR10631. 1 hit.
PfamiPF02005. TRM. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51626. SAM_MT_TRM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRM1_PYRNV
AccessioniPrimary (citable) accession number: B1YCV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.