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Protein
Submitted name:

Orotidine 5'-phosphate decarboxylase

Gene

Tneu_0023

Organism
Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: InterPro

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciTNEU444157:GHL2-23-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Orotidine 5'-phosphate decarboxylaseImported
Gene namesi
Ordered Locus Names:Tneu_0023Imported
OrganismiPyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)Imported
Taxonomic identifieri444157 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000001694 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi444157.Tneu_0023.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DF0X-ray1.50A/B1-202[»]
4DF1X-ray1.90A/B1-202[»]
ProteinModelPortaliB1Y9Q9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000226069.
KOiK01591.
OMAiFEIVGRY.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

B1Y9Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAANLPLVVA LDTEVLKAID VAKRLKGAVA GFKVGWDLIF EGGISIVGEI
60 70 80 90 100
ARYGNVIVDL KIADVPHVAS RVVEKLVNRG ACCVIVHGFL HPSLPRGQHV
110 120 130 140 150
YVLVKMTAPT IYDEMWEKLL NSVQDVRGFV LPGNQPEVVA QARKRIGCSY
160 170 180 190 200
RIISPGIGPQ GGRPGAAIEA GADFEIVGRY VLEDPARISQ WAQYRPTCFE

TP
Length:202
Mass (Da):21,927
Last modified:May 20, 2008 - v1
Checksum:i8039512D14714DE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB38981.1.
RefSeqiYP_001793427.1. NC_010525.1.

Genome annotation databases

EnsemblBacteriaiACB38981; ACB38981; Tneu_0023.
GeneIDi6166266.
KEGGitne:Tneu_0023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB38981.1.
RefSeqiYP_001793427.1. NC_010525.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DF0X-ray1.50A/B1-202[»]
4DF1X-ray1.90A/B1-202[»]
ProteinModelPortaliB1Y9Q9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444157.Tneu_0023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB38981; ACB38981; Tneu_0023.
GeneIDi6166266.
KEGGitne:Tneu_0023.

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000226069.
KOiK01591.
OMAiFEIVGRY.

Enzyme and pathway databases

BioCyciTNEU444157:GHL2-23-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2338 / JCM 9278 / V24StaImported.
  2. "Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP."
    Fedorov A.A., Fedorov E.V., Desai B., Gerlt J.A., Almo S.C.
    Submitted (JAN-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS), ACTIVE SITE.
  3. "Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus."
    Fedorov A.A., Fedorov E.V., Desai B., Gerlt J.A., Almo S.C.
    Submitted (JAN-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS), ACTIVE SITE.

Entry informationi

Entry nameiB1Y9Q9_PYRNV
AccessioniPrimary (citable) accession number: B1Y9Q9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: February 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.