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Protein

Nucleoside-triphosphatase THEP1

Gene

Tneu_1537

Organism
Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.UniRule annotation

Catalytic activityi

NTP + H2O = NDP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22ATPUniRule annotation8
Nucleotide bindingi102 – 109ATPUniRule annotation8

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPNEU444157:G12XQ-1530-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside-triphosphatase THEP1UniRule annotation (EC:3.6.1.15UniRule annotation)
Short name:
NTPase THEP1UniRule annotation
Alternative name(s):
Nucleoside triphosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:Tneu_1537
OrganismiPyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) (Thermoproteus neutrophilus)
Taxonomic identifieri444157 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000001694 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003600311 – 175Nucleoside-triphosphatase THEP1Add BLAST175

Interactioni

Protein-protein interaction databases

STRINGi444157.Tneu_1537.

Structurei

3D structure databases

ProteinModelPortaliB1Y9N2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEP1 NTPase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiELARSKY.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

B1Y9N2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRERAESK VGITGMPGVG KTTLAMEVAN LARRRMTVCG FITLEVREAG
60 70 80 90 100
RRVGFDVYDI STGSRVPLAR VGAGAVTVGK YVVDLSACDV IKRILDAASC
110 120 130 140 150
DLLVVDEIGA MEVKCPNFLV SLEKAVKSSP RVLAVVHRNY LDVAKRLGIE
160 170
VLWLSRENRE AVREEVLRKL GLPLA
Length:175
Mass (Da):19,053
Last modified:May 20, 2008 - v1
Checksum:iF3C2529BCF991497
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB40461.1.

Genome annotation databases

EnsemblBacteriaiACB40461; ACB40461; Tneu_1537.
KEGGitne:Tneu_1537.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001014 Genomic DNA. Translation: ACB40461.1.

3D structure databases

ProteinModelPortaliB1Y9N2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444157.Tneu_1537.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB40461; ACB40461; Tneu_1537.
KEGGitne:Tneu_1537.

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiELARSKY.

Enzyme and pathway databases

BioCyciPNEU444157:G12XQ-1530-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNTPTH_PYRNV
AccessioniPrimary (citable) accession number: B1Y9N2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 20, 2008
Last modified: November 30, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.