ID   B1Y379_LEPCP            Unreviewed;       479 AA.
AC   B1Y379;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE            Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE   AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN   OrderedLocusNames=Lcho_1011 {ECO:0000313|EMBL:ACB33282.1};
OS   Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix
OS   discophora (strain SP-6)).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilaceae; Leptothrix.
OX   NCBI_TaxID=395495 {ECO:0000313|EMBL:ACB33282.1, ECO:0000313|Proteomes:UP000001693};
RN   [1] {ECO:0000313|EMBL:ACB33282.1, ECO:0000313|Proteomes:UP000001693}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51168 / LMG 8142 / SP-6
RC   {ECO:0000313|Proteomes:UP000001693};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Lykidis A., Emerson D., Richardson P.;
RT   "Complete sequence of Leptothrix cholodnii SP-6.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end. {ECO:0000256|RuleBase:RU362066}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC       ECO:0000256|RuleBase:RU362066}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC       Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC       ECO:0000256|RuleBase:RU362066}.
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DR   EMBL; CP001013; ACB33282.1; -; Genomic_DNA.
DR   RefSeq; WP_012346044.1; NC_010524.1.
DR   AlphaFoldDB; B1Y379; -.
DR   STRING; 395495.Lcho_1011; -.
DR   KEGG; lch:Lcho_1011; -.
DR   eggNOG; COG1345; Bacteria.
DR   HOGENOM; CLU_015182_6_1_4; -.
DR   OrthoDB; 9810816at2; -.
DR   Proteomes; UP000001693; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR   PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW   ECO:0000256|RuleBase:RU362066};
KW   Cell projection {ECO:0000313|EMBL:ACB33282.1};
KW   Cilium {ECO:0000313|EMBL:ACB33282.1};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Flagellum {ECO:0000313|EMBL:ACB33282.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001693};
KW   Secreted {ECO:0000256|RuleBase:RU362066}.
FT   DOMAIN          11..107
FT                   /note="Flagellar hook-associated protein 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02465"
FT   DOMAIN          236..461
FT                   /note="Flagellar hook-associated protein 2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07195"
SQ   SEQUENCE   479 AA;  49125 MW;  F11E857B7FA91D05 CRC64;
     MASISSAGIG SGLDVSSIVT QLMAVEKSPL QQMQTEASKI QSKLSAYGKV QSYVSALRDA
     ALNLTKSDTW GSTTASSGDA SVFTATTASG ATAGNYSLTV QQMASAQTVA SAAWPASVST
     VGSGVLRLEL GTWAAGQTGF TPKSGTSSVD VTVAASDTLA DVRDKINAAK SGVMASIVND
     TSGSRLVLRS SETGAENAFR VTATDDDGNN TDASGLSALA FDPSAGANAM VQSQAAVNAR
     ATINGLSVSS ASNLLTDVVD GVTIKLGKVS STPVDLSVSS NTESVKTAVT AFADAYNNLS
     KYLAEQTKYN AAAKSGATLQ GDSGTNALRS AMRNIIGGTS GVTGAFNRLA QVGLDPQSDG
     TLKVDSTKLT SSLGKLADLK ALFANKDAGN EANNGFAVSL QKWGDSLLSF DGSLSTRSSS
     LQRQIDANAK KQEDFNERMT GVEARIRAQY TALDTQMAKL NGLSTYMTQQ ITNMNKSSS
//