B1Y0P9 (GLGA_LEPCP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	Lcho_1890

Organism

Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix discophora (strain SP-6)) [Complete proteome] [HAMAP]

Taxonomic identifier

395495 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Leptothrix

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 487	487	Glycogen synthase HAMAP MF_00484		PRO_1000126085
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1Y0P9 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 36BF73B11A7D2D5E	FASTA	487	53,120
	10 20 30 40 50 60 MRILQACAEI FPLLKTGGLA DVAGALPPAL RALGAEVRVV VPGFPAILAG LVDAIEVARL 70 80 90 100 110 120 EPPPAMVMAR GARLLYGRLP ACDVDAYVIN SPDHYHRDGG PYNDARQHPY DDNHLRFGLL 130 140 150 160 170 180 GWVAAKLADG LDPYWAPRVV HAHDWHAALA PAYLRALEWA RGRRLAGSVY TVHNLAYQGF 190 200 210 220 230 240 FPAHHFGDLG LPAAYNQVHG LEFYGQISFM KGGLYFADRI TTVSPTYARE IQGAEQGCGL 250 260 270 280 290 300 DGLLRDRDAD LSGILNGVDD AVWNPAGDAL IPATYTRRKL TGKAQCKATL QAELGLAEDP 310 320 330 340 350 360 AVPLLCVVSR LTEQKGLHLV LQALPALIER GFQFALLGSG DAGMENEFRR LAEQHPTAAA 370 380 390 400 410 420 VRLGYDEAFA HRLIAGSDLI LVPSRFEPCG LTQLYGLKYG TLPVVRRVGG LVDTVADARL 430 440 450 460 470 480 ETLDHDATGF VFDDFSADGL IGACLRAKAL FRRRADWLQV QRRGMQQPFG WEDSARQYLK LYQQVAA

References

[1]

"Complete sequence of Leptothrix cholodnii SP-6." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Lykidis A., Emerson D., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51168 / LMG 8142 / SP-6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001013 Genomic DNA. Translation: ACB34157.1.
RefSeq	YP_001790922.1. NC_010524.1.
3D structure databases
ProteinModelPortal	B1Y0P9.
ModBase	Search...
Protein-protein interaction databases
STRING	B1Y0P9.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6159917.
GenomeReviews	Gene locus Lcho_1890 in contig CP001013_GR.
KEGG	lch:Lcho_1890.
PATRIC	22394121. VBILepCho83238_1904.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG596384.
OMA	PIVHEIG.
ProtClustDB	PRK00654.
Enzyme and pathway databases
BioCyc	LCHO395495:LCHO_1890-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_LEPCP

Accession

Primary (citable) accession number: B1Y0P9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program