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Reviewed, UniProtKB/Swiss-Prot B1XZ11 (F16A1_LEPCP)

Last modified November 24, 2009. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1 1
      Short name=FBPase class 1 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1
Gene names
Name: fbp1
Ordered Locus Names: Lcho_1763
OrganismLeptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix discophora (strain SP-6)) [Complete proteome] [HAMAP]
Taxonomic identifier395495 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Leptothrix

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Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855
PRO_0000364590

Regions

Region117 – 1204Substrate binding By similarity

Sites

Metal binding921Magnesium 1 By similarity
Metal binding1141Magnesium 1 By similarity
Metal binding1141Magnesium 2 By similarity
Metal binding1161Magnesium 1; via carbonyl oxygen By similarity
Metal binding1171Magnesium 2 By similarity
Metal binding2811Magnesium 2 By similarity
Binding site2091Substrate By similarity
Binding site2751Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
B1XZ11-1 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 37F9A7A2F1987372

FASTA34137,866
        10         20         30         40         50         60 
MSKRISLTQF LVEQQRQHGR IPAQLRLLIE VVARACKRIA ISVNKGALGE VLGSAGSENV 

        70         80         90        100        110        120 
QGEVQKKLDI ISNEVLIEAN EWGGHLAAMA SEEMDSIHVV PNRYPQGEYM LLFDPLDGSS 

       130        140        150        160        170        180 
NIDVNVSIGT IFSVLRKVGH QHGVSEEDFL QPGKFQAAAG YCVYGPQTTL VLTVGDGVAV 

       190        200        210        220        230        240 
FTLDRETGSF VLTQSNLQIP ADTHEFAINA SNHRHWAPPM KRYIDECLAG REGPRGKDFN 

       250        260        270        280        290        300 
MRWVGSMVAD VHRILTRGGI FLYPWDQREP DKPGKLRLMY EANPMAFLVE QAGGAATNGE 

       310        320        330        340 
QRIMDLMPGK LHERVSVMMG SKNEVERVSQ YHREHREAAG H

« Hide

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References

[1]"Complete sequence of Leptothrix cholodnii SP-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Lykidis A., Emerson D., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP001013 Genomic DNA. Translation: ACB34030.1.
RefSeqYP_001790795.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6162060.
GenomeReviewsGene locus Lcho_1763 in contig CP001013_GR.
KEGGlch:Lcho_1763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHWEAPVQ

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16A1_LEPCP
AccessionPrimary (citable) accession number: B1XZ11
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 20, 2008
Last modified: November 24, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents