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B1XZ11 (F16A1_LEPCP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1 1
Short name=FBPase class 1 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1
Gene names
Name:fbp1
Ordered Locus Names:Lcho_1763
OrganismLeptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix discophora (strain SP-6)) [Complete proteome] [HAMAP]
Taxonomic identifier395495 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Leptothrix

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855
PRO_0000364590

Regions

Region117 – 1204Substrate binding By similarity

Sites

Metal binding921Magnesium 1 By similarity
Metal binding1141Magnesium 1 By similarity
Metal binding1141Magnesium 2 By similarity
Metal binding1161Magnesium 1; via carbonyl oxygen By similarity
Metal binding1171Magnesium 2 By similarity
Metal binding2811Magnesium 2 By similarity
Binding site2091Substrate By similarity
Binding site2751Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
B1XZ11 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 37F9A7A2F1987372

FASTA34137,866
        10         20         30         40         50         60 
MSKRISLTQF LVEQQRQHGR IPAQLRLLIE VVARACKRIA ISVNKGALGE VLGSAGSENV 

        70         80         90        100        110        120 
QGEVQKKLDI ISNEVLIEAN EWGGHLAAMA SEEMDSIHVV PNRYPQGEYM LLFDPLDGSS 

       130        140        150        160        170        180 
NIDVNVSIGT IFSVLRKVGH QHGVSEEDFL QPGKFQAAAG YCVYGPQTTL VLTVGDGVAV 

       190        200        210        220        230        240 
FTLDRETGSF VLTQSNLQIP ADTHEFAINA SNHRHWAPPM KRYIDECLAG REGPRGKDFN 

       250        260        270        280        290        300 
MRWVGSMVAD VHRILTRGGI FLYPWDQREP DKPGKLRLMY EANPMAFLVE QAGGAATNGE 

       310        320        330        340 
QRIMDLMPGK LHERVSVMMG SKNEVERVSQ YHREHREAAG H

« Hide

References

[1]"Complete sequence of Leptothrix cholodnii SP-6."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Lykidis A., Emerson D., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51168 / LMG 8142 / SP-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001013 Genomic DNA. Translation: ACB34030.1.
RefSeqYP_001790795.1. NC_010524.1.

3D structure databases

ProteinModelPortalB1XZ11.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1XZ11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6162060.
GenomeReviewsGene locus Lcho_1763 in contig CP001013_GR.
KEGGlch:Lcho_1763.
PATRIC22393863. VBILepCho83238_1775.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMAHWEAPVQ.
ProtClustDBPRK09293.

Enzyme and pathway databases

BioCycLCHO395495:LCHO_1763-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16A1_LEPCP
AccessionPrimary (citable) accession number: B1XZ11
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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