B1XYE3 (B1XYE3_LEPCP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	Lcho_2923

Organism

Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix discophora (strain SP-6)) [Complete proteome] [HAMAP] EMBL ACB35188.1

Taxonomic identifier

395495 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Leptothrix

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ACB35188.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	26	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	B1XYE3 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 9A36BFAF34C5CFD5	FASTA	191	21,068
	10 20 30 40 50 60 MSASPSDPTT PAAAKPAETI TLGGGCFWCL EAVFLQVEGV ESVQSGYTNG RVVNPGYEAV 70 80 90 100 110 120 CGGDTGHAEV VQLRFSPDVI DLAELLRIFF VIHDPTTLNR QGHDVGTQYR SGIYWHDPKQ 130 140 150 160 170 180 VEVAKAVMQE AGQAWSAPIV TELLALDNYW PAEAYHQRYF ENHPGQGYCA YVIAPKVNKF 190 RQAFARHQRK G

References

[1]

"Complete sequence of Leptothrix cholodnii SP-6." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Lykidis A., Emerson D., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51168 / LMG 8142 / SP-6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001013 Genomic DNA. Translation: ACB35188.1.
RefSeq	YP_001791953.1. NC_010524.1.
3D structure databases
ProteinModelPortal	B1XYE3.
ModBase	Search...
Protein-protein interaction databases
STRING	B1XYE3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6160263.
GenomeReviews	Gene locus Lcho_2923 in contig CP001013_GR.
KEGG	lch:Lcho_2923.
PATRIC	22396259. VBILepCho83238_2955.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748152.
OMA	IDTEVGY.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1XYE3_LEPCP

Accession

Primary (citable) accession number: B1XYE3

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)