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B1XW11

- SYQ_POLNS

UniProt

B1XW11 - SYQ_POLNS

Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Polynucleobacter necessarius subsp. necessarius (strain STIR1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei302 – 3021ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutaminyl-tRNA aminoacylation Source: InterPro
    2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPNEC452638:GI4T-1439-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
    Alternative name(s):
    Glutaminyl-tRNA synthetaseUniRule annotation
    Short name:
    GlnRSUniRule annotation
    Gene namesi
    Name:glnSUniRule annotation
    Ordered Locus Names:Pnec_1440
    OrganismiPolynucleobacter necessarius subsp. necessarius (strain STIR1)
    Taxonomic identifieri452638 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaePolynucleobacter
    ProteomesiUP000006582: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 590590Glutamine--tRNA ligasePRO_1000095496Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi452638.Pnec_1440.

    Structurei

    3D structure databases

    ProteinModelPortaliB1XW11.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi55 – 6511"HIGH" regionAdd
    BLAST
    Motifi299 – 3035"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0008.
    HOGENOMiHOG000259232.
    KOiK01886.
    OMAiKSDSWID.
    OrthoDBiEOG6DRPF7.

    Family and domain databases

    Gene3Di1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPiMF_00126. Gln_tRNA_synth.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50715. SSF50715. 1 hit.
    TIGRFAMsiTIGR00440. glnS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1XW11-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQDSKPSKA NAGAVVEPSN FLRQIIDHDL ASGAFSQRTN LAGEAIPSII    50
    TRFPPEPNGY LHIGHAKSIC LNFGLASDYN NQPGGARCNM RLDDTNPVKE 100
    DVEYADSILD AVKWLGFDWG THLYHASDYF DRLYEFAEIL IQSGKAYVDS 150
    QSADDIHTNR GNFGQAGKNS PFRDRTPEEN LQLFRDMRDG KFKDGEHVLR 200
    LKIDMAHPNI VMRDPVVYRI RHTDHHRTGS KWCIYPLYDF THCISDALEN 250
    ISHSICTLEF ENNRPLYDWI VNSLKELGVF KDPVPHQHEF ARLNLTYTIT 300
    SKRKLLQLVE EKHVEGWDDP RMPTIVGIRR RGYTPESIRL FCERIGVSKA 350
    DSWIDMSTLD QALRDDLEVR APRATAVLKP LKLVVENFDA PTKEACSAPR 400
    HPNYPEWGNR EFNFTRELWI EADDFMQEPI KGFFRLYPPI DDQPGSRVRL 450
    RHGFVVECTG FETDAQGNVT QVNVTHFPDS KSGTPGSNNY KVKGNIHWIS 500
    AAEAIPAEVR LYDHLFTDPY PDSGDKNFLD AINPNSKQTI SAYLEPCMKD 550
    AKAEDRFQFE RHGYFVADQS DSKPGKPIFN RAVGLKDSWK 590
    Length:590
    Mass (Da):67,311
    Last modified:May 20, 2008 - v1
    Checksum:i72A5635BB5F03842
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001010 Genomic DNA. Translation: ACB44538.1.
    RefSeqiYP_001798152.1. NC_010531.1.

    Genome annotation databases

    EnsemblBacteriaiACB44538; ACB44538; Pnec_1440.
    GeneIDi6183594.
    KEGGipne:Pnec_1440.
    PATRICi22972109. VBIPolNec8289_1653.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001010 Genomic DNA. Translation: ACB44538.1 .
    RefSeqi YP_001798152.1. NC_010531.1.

    3D structure databases

    ProteinModelPortali B1XW11.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 452638.Pnec_1440.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB44538 ; ACB44538 ; Pnec_1440 .
    GeneIDi 6183594.
    KEGGi pne:Pnec_1440.
    PATRICi 22972109. VBIPolNec8289_1653.

    Phylogenomic databases

    eggNOGi COG0008.
    HOGENOMi HOG000259232.
    KOi K01886.
    OMAi KSDSWID.
    OrthoDBi EOG6DRPF7.

    Enzyme and pathway databases

    BioCyci PNEC452638:GI4T-1439-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPi MF_00126. Gln_tRNA_synth.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50715. SSF50715. 1 hit.
    TIGRFAMsi TIGR00440. glnS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: STIR1.

    Entry informationi

    Entry nameiSYQ_POLNS
    AccessioniPrimary (citable) accession number: B1XW11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3