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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Polynucleobacter necessarius subsp. necessarius (strain STIR1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Pnec_1686
OrganismiPolynucleobacter necessarius subsp. necessarius (strain STIR1)
Taxonomic identifieri452638 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaePolynucleobacter
Proteomesi
  • UP000006582 Componenti: Chromosome

Subcellular locationi

B1XSF4:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953891 – 575Arginine--tRNA ligaseAdd BLAST575

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi452638.Pnec_1686.

Structurei

3D structure databases

ProteinModelPortaliB1XSF4.
SMRiB1XSF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi136 – 146"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B1XSF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSTNKNRLI EMLSAALTGL AQERGLEAPP TPRLERPKAV DHGDVACNIA
60 70 80 90 100
LQLSKAWKLN PRELAQALVE RLQQQTGFNE LIASCEIAGP GFSNFRLSNA
110 120 130 140 150
AKTAVVQEIL SGGTSFGESA PADGSATSAM IEFVSANPTG PLHVGHGRQA
160 170 180 190 200
ALGDALANLL ATQGIKVHRE FYYNDAGVQI ANLALSVQAR LQGLKPGDAK
210 220 230 240 250
WPEQAYNGEY IAEIATTFKA SPEFKDDIEA IRQFAVAYLR NEQDIDLKTF
260 270 280 290 300
GVKFDCYYLE SSLYTDGSVA QIVGDLQSIG KTYESEGVLW LKTIDDGDDK
310 320 330 340 350
DRVMRKSDGS FTYFVPDVAY HTSKWNRGFQ KVINVQGSDH HGTIARVRSG
360 370 380 390 400
LQGVAQKRGW DIPKTYPDYV LHKMVTVMRH GEEVKISKRA GSYVTVRDLV
410 420 430 440 450
EWSGGVTPEM TSEERELALQ RGRDAVRFFL ISRKADTEFV FDIDLALQQN
460 470 480 490 500
DENPVFYVQY AHARISSILQ QWGGQTSDLA SADLSLLQSK ASDHLLRCLA
510 520 530 540 550
EYPEMLTTAA EELAPHALAF YLRNLAGDFH TFYNADRVLV DDQNLKLARL
560 570
ALLSATRQVL QNGLKVLGVS APAKM
Length:575
Mass (Da):63,379
Last modified:May 20, 2008 - v1
Checksum:i477C70D429FB3BA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001010 Genomic DNA. Translation: ACB44753.1.
RefSeqiWP_012358511.1. NC_010531.1.

Genome annotation databases

EnsemblBacteriaiACB44753; ACB44753; Pnec_1686.
KEGGipne:Pnec_1686.

Similar proteinsi

Entry informationi

Entry nameiSYR_POLNS
AccessioniPrimary (citable) accession number: B1XSF4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families