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B1XRU3 (B1XRU3_POLNS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Pnec_1486
OrganismPolynucleobacter necessarius (strain STIR1) [Complete proteome] [HAMAP]
Taxonomic identifier452638 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Polynucleobacter

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2101Iron By similarity HAMAP MF_00323
Metal binding2911Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B1XRU3 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: A1804A86F793FFA1

FASTA36441,274
        10         20         30         40         50         60 
MNPNPHLRAS KTAVLLLNLG TPSAPTPKAV RAYLKEFLSD RRVVEIPRII WWCILNGIIL 

        70         80         90        100        110        120 
SIRSSASAKK YASIWLPKLG SPLMHYSRLQ AKELGEIFAN EGHTVLVDLA MRYGQPSTQS 

       130        140        150        160        170        180 
VLEGLKAQGM ERLLLLPLYP QYSATTTASS FDEVFRVLST WRDQPELRLV KHYHDSPAYI 

       190        200        210        220        230        240 
SALRDQVLSS WDANGRPDFA KGDRFVMSFH GLPKRNLMKG DPYHCECLKT GRLLGESLGL 

       250        260        270        280        290        300 
EPGQYIVAFQ SRFGKSEWLK PYTAPTIEKL AKEGCQWLDI FCPGFPADCL ETLEEIAMEA 

       310        320        330        340        350        360 
REIFLEHGGK DYRYIPCLDS NPRWIEALRD IAHHHLQGWP LGVEPQAELA KRAERAELVE 


KAKY

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References

[1]"Complete sequence of Polynucleobacter necessarius STIR1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Hahn M., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: STIR1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001010 Genomic DNA. Translation: ACB44578.1.
RefSeqYP_001798192.1. NC_010531.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB1XRU3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6183747.
GenomeReviewsGene locus Pnec_1486 in contig CP001010_GR.
KEGGpne:Pnec_1486.
PATRIC22972220. VBIPolNec8289_1708.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMAIRPAKSA.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1XRU3_POLNS
AccessionPrimary (citable) accession number: B1XRU3
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info