Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1XQ34 (B1XQ34_SYNP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333
Short name=Coprogen oxidase HAMAP MF_00333
Short name=Coproporphyrinogenase HAMAP MF_00333
EC=1.3.3.3 HAMAP MF_00333
Gene names
Name:hemF HAMAP MF_00333 EMBL ACA99816.1
Ordered Locus Names:SYNPCC7002_A1828
OrganismSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]
Taxonomic identifier32049 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. HAMAP MF_00333 SAAS SAAS018375

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333 SAAS SAAS018375

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333 SAAS SAAS018375

Subunit structure

Homodimer By similarity. HAMAP MF_00333 SAAS SAAS018375

Subcellular location

Cytoplasm By similarity HAMAP MF_00333.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family. HAMAP MF_00333

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region67 – 7610Important for dimerization By similarity HAMAP MF_00333
Region127 – 1293Substrate binding By similarity HAMAP MF_00333
Region280 – 31536Important for dimerization By similarity HAMAP MF_00333
Region298 – 3036Substrate binding By similarity HAMAP MF_00333

Sites

Active site1251Proton donor By similarity HAMAP MF_00333
Binding site1111Substrate By similarity HAMAP MF_00333
Site1891Important for dimerization By similarity HAMAP MF_00333

Sequences

Sequence LengthMass (Da)Tools
B1XQ34 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: D99659379F7F025A

FASTA34439,650
        10         20         30         40         50         60 
MTALQTESTN ASSAKPVPPS DSKERVSQFM QQIQDKICQG LEVADGKGKF QEDSWQRQEG 

        70         80         90        100        110        120 
GGGRSRVMRE GNVLEQGGVN FSEVWGDQLP PSILKQRPEA AGHGFYATGT SMVLHPRNPY 

       130        140        150        160        170        180 
IPTVHLNYRY FEAGPVWWFG GGADLTPYYP FAEDAAHFHK TYQAACDRHH KEYYNVFKRW 

       190        200        210        220        230        240 
CDEYFYLKHR DETRGVGGLF FDYQDGTGEL YKGPHPDKAA AAYSKDLGEQ PQRSWEDIFA 

       250        260        270        280        290        300 
FVQDCGGSFL DSYVPIIERR RNTEYGDRER QFQLYRRGRY VEFNLVYDRG TIFGLQTNGR 

       310        320        330        340 
TESILMSLPP LVRWEYSYSP EPGTPEAELY ERFLKPQDWA NWQG

« Hide

References

[1]"Complete sequence of Synechococcus sp. PCC 7002."
Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000951 Genomic DNA. Translation: ACA99816.1.
RefSeqYP_001735072.1. NC_010475.1.

3D structure databases

ProteinModelPortalB1XQ34.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1XQ34.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6057309.
GenomeReviewsGene locus SYNPCC7002_A1828 in contig CP000951_GR.
KEGGsyp:SYNPCC7002_A1828.
PATRIC23818292. VBISynSp37135_2087.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG631180.
OMAVKAYLLD.
PhylomeDBB1XQ34.
ProtClustDBPRK05330.

Family and domain databases

HAMAPMF_00333. Coprogen_oxidas.
[Tree]
InterProIPR001260. Coprogen_oxidase_aer.
IPR018375. Coprogen_oxidase_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KOK00228.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 2 hits.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
SUPFAMSSF102886. Coprogen_oxidas. 1 hit.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1XQ34_SYNP2
AccessionPrimary (citable) accession number: B1XQ34
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info