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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:SYNPCC7002_A1703
OrganismiSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Taxonomic identifieri32049 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001688 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001256471 – 363AminomethyltransferaseAdd BLAST363

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi32049.SYNPCC7002_A1703

Structurei

3D structure databases

ProteinModelPortaliB1XP99
SMRiB1XP99
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiMPVQYPA
OrthoDBiPOG091H04FV

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

B1XP99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQRTPLHD LAIAAGAKFV PFSGWEMAVQ YKGLKVEHQA VRTEVGMFDI
60 70 80 90 100
SHMGKFQLAG ENLIAAMQKL VPSNLARLAP GQAQYTVLLN DHGGIIDDVI
110 120 130 140 150
YYHQGDRQGF LIVNAATTQK DWDWLTHHLT AQGITLTDVS QENILLAIQG
160 170 180 190 200
PQAEKALQPV VENLDLATLK LFNHGQGQIF GETAFIARTG YTGEDGFEVM
210 220 230 240 250
VAPTAGKKLW SALIDAGVMP CGLGARDTLR LEAGLHLYGQ DMDDDTTPLE
260 270 280 290 300
AGLGWLIHWQ EKDAFIAKDI LQTQKAAGVQ RRLVGLEMQG RGIARHDYSV
310 320 330 340 350
LVNGEAVGLV TSGTMSPTLE KAIALAYLPL EFSKVGQAVT VEIRGKQYPA
360
QVVKKPFYRA SKK
Length:363
Mass (Da):39,644
Last modified:May 20, 2008 - v1
Checksum:iBA8A4980A591CC99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000951 Genomic DNA Translation: ACA99692.1
RefSeqiWP_012307315.1, NC_010475.1

Genome annotation databases

EnsemblBacteriaiACA99692; ACA99692; SYNPCC7002_A1703
KEGGisyp:SYNPCC7002_A1703

Similar proteinsi

Entry informationi

Entry nameiGCST_SYNP2
AccessioniPrimary (citable) accession number: B1XP99
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 20, 2008
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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