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B1XNF1 (B1XNF1_SYNP2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase HAMAP MF_00388

EC=3.5.1.- HAMAP MF_00388
Alternative name(s):
UDP-3-O-acyl-GlcNAc deacetylase HAMAP MF_00388
Gene names
Name:lpxC HAMAP MF_00388 EMBL ACA98329.1
Ordered Locus Names:SYNPCC7002_A0319
OrganismSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]
Taxonomic identifier32049 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaChroococcalesSynechococcus

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00388 SAAS SAAS015870

Catalytic activity

UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. HAMAP MF_00388 SAAS SAAS015870

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. HAMAP MF_00388 SAAS SAAS015870

Sequence similarities

Belongs to the LpxC family. HAMAP MF_00388

Sequences

Sequence LengthMass (Da)Tools
B1XNF1 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 0877F4EB2AAEEAE4

FASTA27530,051
        10         20         30         40         50         60 
MVKTLKTTVE CSGVGLHSGQ RVTLRLVPGD RHQGRYFVRT DLPGQPQIPA RIEAVDQTLL 

        70         80         90        100        110        120 
STELAVGEAK VRTTEHLLAA LVGLGIDVVR LEIDGPELPL LDGSAAQWVE AIAKAGTQTL 

       130        140        150        160        170        180 
TDEAIAVPVV AEPVWLREDD AFVVALPSLE LRFTYGIDFT YKPIGNQWHS WSPAAEPFAQ 

       190        200        210        220        230        240 
AIAPARTFGF ADQIEQLKKA GLIQGGSLDN ALVCDQEKWL NPPLRFDNEP ARHKLLDLIG 

       250        260        270 
DLSLLGTIPT AHYLAYKASH KLHTQLAKTL QAMLF 

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References

[1]"Complete sequence of Synechococcus sp. PCC 7002."
Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000951 Genomic DNA. Translation: ACA98329.1.
RefSeqYP_001733585.1. NC_010475.1.

3D structure databases

ProteinModelPortalB1XNF1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1XNF1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6056673.
GenomeReviewsGene locus SYNPCC7002_A0319 in contig CP000951_GR.
KEGGsyp:SYNPCC7002_A0319.
PATRIC23815078. VBISynSp37135_0502.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG482342.
OMAKAYKSGH.
PhylomeDBB1XNF1.
ProtClustDBPRK13186.

Family and domain databases

HAMAPMF_00388. LpxC.
[Tree]
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR004463. UDP-acyl_GlcNac_deAcase.
IPR011334. UDP-acyl_GlcNac_deAcase_C.
IPR015870. UDP-acyl_N-AcGlcN_deAcase_N.
[Graphical view]
Gene3DG3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit.
G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KOK02535.
PfamPF03331. LpxC. 1 hit.
[Graphical view]
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMsTIGR00325. LpxC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1XNF1_SYNP2
AccessionPrimary (citable) accession number: B1XNF1
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)