Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1XKA0 (AROB_SYNP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:SYNPCC7002_A1146
OrganismSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]
Taxonomic identifier32049 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3653653-dehydroquinate synthase HAMAP MF_00110
PRO_1000094645

Sequences

Sequence LengthMass (Da)Tools
B1XKA0 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 1BB71A2D05ED8A3F

FASTA36539,526
        10         20         30         40         50         60 
MDATTRVELG ENSYDIAIAK ESLQQIGTFL RPLDLGQKVL IVSNPEIYGH YGETVVNSLQ 

        70         80         90        100        110        120 
AAGFSVDTHL IPAGEQYKNL ASIEKIYDTA FKNRLERSST LLALGGGVIG DMTGFAAATW 

       130        140        150        160        170        180 
LRGINFVQVP TTLLAMVDAS VGGKTGVNHP QGKNLIGAFY QPKFVLIDPT VLKTLPVREF 

       190        200        210        220        230        240 
RAGMAEVIKY GVIWDADLFT KLEAAEQIDS YATIDPDLLD LILERSCRAK AEVVSQDERE 

       250        260        270        280        290        300 
SGLRAILNYG HTLGHAVESL THYETFVHGE GVAIGMALAG AIATRMNLWT TAETQRQDAL 

       310        320        330        340        350        360 
IKKAGLPTEC PNNLAIEAIL ETLQSDKKVK SGKVRFVLPT KIGEVLITDQ VSADLITDVL 


APALC

« Hide

References

[1]"Complete sequence of Synechococcus sp. PCC 7002."
Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27264 / PCC 7002 / PR-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000951 Genomic DNA. Translation: ACA99146.1.
RefSeqYP_001734402.1. NC_010475.1.

3D structure databases

ProteinModelPortalB1XKA0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1XKA0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6057782.
GenomeReviewsGene locus SYNPCC7002_A1146 in contig CP000951_GR.
KEGGsyp:SYNPCC7002_A1146.
PATRIC23816826. VBISynSp37135_1366.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBB1XKA0.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_SYNP2
AccessionPrimary (citable) accession number: B1XKA0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents