ID   B1XK84_PICP2            Unreviewed;       868 AA.
AC   B1XK84;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=Two-component response regulator (ABC transporter) / (GGDEF domain protein) {ECO:0000313|EMBL:ACB00439.1};
GN   OrderedLocusNames=SYNPCC7002_A2461 {ECO:0000313|EMBL:ACB00439.1};
OS   Picosynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum
OS   quadruplicatum).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Geminocystaceae; Picosynechococcus.
OX   NCBI_TaxID=32049 {ECO:0000313|EMBL:ACB00439.1, ECO:0000313|Proteomes:UP000001688};
RN   [1] {ECO:0000313|Proteomes:UP000001688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6
RC   {ECO:0000313|Proteomes:UP000001688};
RA   Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T.,
RA   Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J.,
RA   Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.;
RT   "Complete sequence of Synechococcus sp. PCC 7002.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000951; ACB00439.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1XK84; -.
DR   STRING; 32049.SYNPCC7002_A2461; -.
DR   KEGG; syp:SYNPCC7002_A2461; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_36_3; -.
DR   Proteomes; UP000001688; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00062; PBPb; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001688};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..868
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002770121"
FT   TRANSMEM        264..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..375
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          377..429
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          462..595
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          604..857
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          287..314
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   868 AA;  99589 MW;  B2FD0FB04CA7BA9C CRC64;
     MNKSTVLLAL GLAAMLSGTE AIAQNQPAKT ITVGVYQNDP KVFIDSGGRA RGFWVDITSD
     IGRVENWAVT YVPCEWNQCL QQIEQGQLDL MVDVAYSDTR DEVFDFNTII VLSSWSQIYA
     RRGVYLETIL DLDQRRVSIL ASGIQQEVLR ERIKAYGIQP ELVPIDSYPG MFEQLETGEV
     DAAIVNNFFG NKFSPDYPVN KTNILFNPAR LHYVVPEGDP KQLLPGIDRQ MSRLLQDRDS
     VYYQAIAQWL EPPETFNWLS LQNFFFSLIV YLPFLFLGWF ILRNYSLKKE IKRRNQIETN
     LLESQQRYAN LANTVSIGIF RTNLRHECIY VNDYYCKLLA IQPEEALHKG WLEKVYPDDI
     DYVREQWLKS ITNQELFTLE YRFQRSDGSI LWVYGQGTAE LDSKGEPQGY VATITDISTR
     IKMEQQLKHD ALHDRLTGLA NRNLLIERLN LALKRYKRYP IHEFAALFLD LDNFKVVNDS
     LGHVVGDELL IEVAHLLKSF IRDTDVAARL GGDEFVILLE EIHGVEDAVH IADRILNALN
     MPFQISNYGV FITTSIGIII GDSRHESAQD LLRDADIAMY RAKQNGKSQY AIFDPQMHLQ
     AMQRLQLEGE IRSAIEEKQF VLYYQPIINL EQGNIEGFEA LIRWQHPQRG LLSPYEFIDV
     AEETGLIIPL GEWILDAACR QLFEWQQAFK TPLKVHVNLS VKQLQDSLLF SLDRLLERYP
     VFPNTLGLEI TESMLIQNID ITCRLLNQIR LKGVFISVDD FGTGYSCLSY LHQLPIDALK
     IDRSFVNISE LNDRNRVIAE SILALSKSIG IKTVAEGIET KQQYQWLKSQ DCQFGQGYLF
     SRPVSLDQAT DLLQGHSFEV LEKLRSSS
//