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B1XHR0 (B1XHR0_SYNP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF EMBL ACA99978.1
Synonyms:acsF2 HAMAP MF_01840
Ordered Locus Names:SYNPCC7002_A1992
OrganismSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]
Taxonomic identifier32049 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B1XHR0 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 5ED6FF84FFBACF0F

FASTA35842,669
        10         20         30         40         50         60 
MVTLTDQPSP ELLRPGVKKP VQETLLTPRF YTTDFDKIAN MVLSSHEEEI LAALEELRAD 

        70         80         90        100        110        120 
YNRNHFIRDE SFEQSWDHFD EKTRSIFIDF LERSCTSEFS GFLLFKELSR RLRDRSPILA 

       130        140        150        160        170        180 
EAFHLLARDE ARHAGFINKS MVDFGLCLDL KYLTQKRTYT FFPPEWVIYT VYLSEKIGYW 

       190        200        210        220        230        240 
RYILVYRHLE KHPEHNIYPL FKYFESWCQD ENRHGDFFKA LLRSQKSLWK TWQSRLWSRF 

       250        260        270        280        290        300 
FLLTVFVTHS LTTLERSDFY EMIGLDAHQY NRDVIRNTNE TSLRAFPEVL DTNHPQFFTR 

       310        320        330        340        350 
LEACAAANEH LKAIATNGNP KVIQFFQKIP WIINIVWHMA LIFFTKPVDA EALRAEVH

« Hide

References

[1]"Complete sequence of Synechococcus sp. PCC 7002."
Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000951 Genomic DNA. Translation: ACA99978.1.
RefSeqYP_001735234.1. NC_010475.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB1XHR0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6057327.
GenomeReviewsGene locus SYNPCC7002_A1992 in contig CP000951_GR.
KEGGsyp:SYNPCC7002_A1992.
PATRIC23818622. VBISynSp37135_2250.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMANRHGDIF.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1XHR0_SYNP2
AccessionPrimary (citable) accession number: B1XHR0
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info