B1XGT8 (B1XGT8_ECODH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tartronate semialdehyde reductase EMBL ACB04205.1

Gene names

Name:	garR EMBL ACB04205.1
Ordered Locus Names:	ECDH10B_3298

Organism

Escherichia coli (strain K12 / DH10B) [Complete proteome] [HAMAP]

Taxonomic identifier

316385 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: InterPro 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1XGT8 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: F5F6A782B0F7F0BE	FASTA	296	30,660
	10 20 30 40 50 60 MTMKVGFIGL GIMGKPMSKN LLKAGYSLVV ADRNPEAIAD VIAAGAETAS TAKAIAEQCD 70 80 90 100 110 120 VIITMLPNSP HVKEVALGEN GIIEGAKPGT VLIDMSSIAP LASREISEAL KAKGIDMLDA 130 140 150 160 170 180 PVSGGEPKAI DGTLSVMVGG DKAIFDKYYD LMKAMAGSVV HTGEIGAGNV TKLANQVIVA 190 200 210 220 230 240 LNIAAMSEAL TLATKAGVNP DLVYQAIRGG LAGSTVLDAK APMVMDRNFK PGFRIDLHIK 250 260 270 280 290 DLANALDTSH GVGAQLPLTA AVMEMMQALR ADGLGTADHS ALACYYEKLA KVEVTR

References

[1]

"The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse." Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B., Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B., Posfai G., Weinstock G.M., Blattner F.R. J. Bacteriol. 190:2597-2606(2008) [PubMed: 18245285] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000948 Genomic DNA. Translation: ACB04205.1.
RefSeq	YP_001731983.1. NC_010473.1.
3D structure databases
ProteinModelPortal	B1XGT8.
SMR	B1XGT8. Positions 3-296.
ModBase	Search...
Protein-protein interaction databases
STRING	B1XGT8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000010285; EBESCP00000009813; EBESCG00000009347.
GeneID	6062429.
GenomeReviews	Gene locus ECDH10B_3298 in contig CP000948_GR.
KEGG	ecd:ECDH10B_3298.
PATRIC	18466519. VBIEscCol59506_3322.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009837.
HOGENOM	HBG729179.
OMA	WSRRRES.
ProtClustDB	PRK11559.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1XGT8_ECODH

Accession

Primary (citable) accession number: B1XGT8

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)