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B1XGB5

- B1XGB5_ECODH

UniProt

B1XGB5 - B1XGB5_ECODH

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Protein
Submitted name:

Ureidoglycolate dehydrogenase

Gene

allD

Organism
Escherichia coli (strain K12 / DH10B)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei44 – 441NADImported
Binding sitei140 – 1401NADImported
Binding sitei158 – 1581NADImported
Binding sitei224 – 2241NADImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi116 – 1183NADImported
Nucleotide bindingi174 – 1763NADImported
Nucleotide bindingi306 – 3083NADImported

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseSAAS annotation

Keywords - Ligandi

NADImported, Nucleotide-bindingImported

Enzyme and pathway databases

BioCyciECOL316385:GJ8B-463-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Ureidoglycolate dehydrogenaseImported
Gene namesi
Name:allDImported
Ordered Locus Names:ECDH10B_0473Imported
OrganismiEscherichia coli (strain K12 / DH10B)Imported
Taxonomic identifieri316385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001689: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi316385.ECDH10B_0473.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FJSX-ray2.13A/B1-349[»]
4FJUX-ray1.77A/B1-349[»]
ProteinModelPortaliB1XGB5.
SMRiB1XGB5. Positions 1-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2055.
HOGENOMiHOG000173270.
KOiK00073.
OMAiMMVDVLS.
OrthoDBiEOG6ZPSZJ.

Family and domain databases

InterProiIPR003767. Malate/L-lactate_DH.
IPR017590. Ureidoglycolate_dehydrogenase.
[Graphical view]
PANTHERiPTHR11091. PTHR11091. 1 hit.
PfamiPF02615. Ldh_2. 1 hit.
[Graphical view]
SUPFAMiSSF89733. SSF89733. 1 hit.
TIGRFAMsiTIGR03175. AllD. 1 hit.

Sequencei

Sequence statusi: Complete.

B1XGB5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKISRETLHQ LIENKLCQAG LKREHAATVA EVLVYADARG IHSHGAVRVE
60 70 80 90 100
YYAERISKGG TNREPEFRLE ETGPCSAILH ADNAAGQVAA KMGMEHAIKT
110 120 130 140 150
AQQNGVAVVG ISRMGHSGAI SYFVQQAARA GFIGISMCQS DPMVVPFGGA
160 170 180 190 200
EIYYGTNPLA FAAPGEGDEI LTFDMATTVQ AWGKVLDARS RNMSIPDTWA
210 220 230 240 250
VDKNGVPTTD PFAVHALLPA AGPKGYGLMM MIDVLSGVLL GLPFGRQVSS
260 270 280 290 300
MYDDLHAGRN LGQLHIVINP NFFSSSELFR QHLSQTMREL NAITPAPGFN
310 320 330 340
QVYYPGQDQD IKQRKAAVEG IEIVDDIYQY LISDALYNTS YETKNPFAQ
Length:349
Mass (Da):37,967
Last modified:May 20, 2008 - v1
Checksum:i93C3076A66141C4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000948 Genomic DNA. Translation: ACB01642.1.
RefSeqiYP_001729420.1. NC_010473.1.

Genome annotation databases

EnsemblBacteriaiACB01642; ACB01642; ECDH10B_0473.
GeneIDi6059947.
KEGGiecd:ECDH10B_0473.
PATRICi18460722. VBIEscCol59506_0479.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000948 Genomic DNA. Translation: ACB01642.1 .
RefSeqi YP_001729420.1. NC_010473.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4FJS X-ray 2.13 A/B 1-349 [» ]
4FJU X-ray 1.77 A/B 1-349 [» ]
ProteinModelPortali B1XGB5.
SMRi B1XGB5. Positions 1-337.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316385.ECDH10B_0473.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB01642 ; ACB01642 ; ECDH10B_0473 .
GeneIDi 6059947.
KEGGi ecd:ECDH10B_0473.
PATRICi 18460722. VBIEscCol59506_0479.

Phylogenomic databases

eggNOGi COG2055.
HOGENOMi HOG000173270.
KOi K00073.
OMAi MMVDVLS.
OrthoDBi EOG6ZPSZJ.

Enzyme and pathway databases

BioCyci ECOL316385:GJ8B-463-MONOMER.

Family and domain databases

InterProi IPR003767. Malate/L-lactate_DH.
IPR017590. Ureidoglycolate_dehydrogenase.
[Graphical view ]
PANTHERi PTHR11091. PTHR11091. 1 hit.
Pfami PF02615. Ldh_2. 1 hit.
[Graphical view ]
SUPFAMi SSF89733. SSF89733. 1 hit.
TIGRFAMsi TIGR03175. AllD. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse."
    Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B., Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B., Posfai G., Weinstock G.M., Blattner F.R.
    J. Bacteriol. 190:2597-2606(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / DH10BImported.
  2. "Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization."
    Kim M.I., Shin I., Cho S., Lee J., Rhee S.
    PLoS ONE 7:e52066-e52066(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.77 ANGSTROMS) IN COMPLEX WITH NAD.

Entry informationi

Entry nameiB1XGB5_ECODH
AccessioniPrimary (citable) accession number: B1XGB5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: October 1, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3