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B1XGB5

- B1XGB5_ECODH

UniProt

B1XGB5 - B1XGB5_ECODH

Protein
Submitted name:

Ureidoglycolate dehydrogenase

Gene

allD

Organism
Escherichia coli (strain K12 / DH10B)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei44 – 441NADImported
    Binding sitei140 – 1401NADImported
    Binding sitei158 – 1581NADImported
    Binding sitei224 – 2241NADImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi116 – 1183NADImported
    Nucleotide bindingi174 – 1763NADImported
    Nucleotide bindingi306 – 3083NADImported

    GO - Molecular functioni

    1. nucleotide binding Source: UniProtKB-KW
    2. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseSAAS annotation

    Keywords - Ligandi

    NADImported, Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciECOL316385:GJ8B-463-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ureidoglycolate dehydrogenaseImported
    Gene namesi
    Name:allDImported
    Ordered Locus Names:ECDH10B_0473Imported
    OrganismiEscherichia coli (strain K12 / DH10B)Imported
    Taxonomic identifieri316385 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001689: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi316385.ECDH10B_0473.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4FJSX-ray2.13A/B1-349[»]
    4FJUX-ray1.77A/B1-349[»]
    ProteinModelPortaliB1XGB5.
    SMRiB1XGB5. Positions 1-337.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG2055.
    HOGENOMiHOG000173270.
    KOiK00073.
    OMAiMMVDVLS.
    OrthoDBiEOG6ZPSZJ.

    Family and domain databases

    InterProiIPR003767. Malate/L-lactate_DH.
    IPR017590. Ureidoglycolate_dehydrogenase.
    [Graphical view]
    PANTHERiPTHR11091. PTHR11091. 1 hit.
    PfamiPF02615. Ldh_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF89733. SSF89733. 1 hit.
    TIGRFAMsiTIGR03175. AllD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B1XGB5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKISRETLHQ LIENKLCQAG LKREHAATVA EVLVYADARG IHSHGAVRVE    50
    YYAERISKGG TNREPEFRLE ETGPCSAILH ADNAAGQVAA KMGMEHAIKT 100
    AQQNGVAVVG ISRMGHSGAI SYFVQQAARA GFIGISMCQS DPMVVPFGGA 150
    EIYYGTNPLA FAAPGEGDEI LTFDMATTVQ AWGKVLDARS RNMSIPDTWA 200
    VDKNGVPTTD PFAVHALLPA AGPKGYGLMM MIDVLSGVLL GLPFGRQVSS 250
    MYDDLHAGRN LGQLHIVINP NFFSSSELFR QHLSQTMREL NAITPAPGFN 300
    QVYYPGQDQD IKQRKAAVEG IEIVDDIYQY LISDALYNTS YETKNPFAQ 349
    Length:349
    Mass (Da):37,967
    Last modified:May 20, 2008 - v1
    Checksum:i93C3076A66141C4E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000948 Genomic DNA. Translation: ACB01642.1.
    RefSeqiYP_001729420.1. NC_010473.1.

    Genome annotation databases

    EnsemblBacteriaiACB01642; ACB01642; ECDH10B_0473.
    GeneIDi6059947.
    KEGGiecd:ECDH10B_0473.
    PATRICi18460722. VBIEscCol59506_0479.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000948 Genomic DNA. Translation: ACB01642.1 .
    RefSeqi YP_001729420.1. NC_010473.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4FJS X-ray 2.13 A/B 1-349 [» ]
    4FJU X-ray 1.77 A/B 1-349 [» ]
    ProteinModelPortali B1XGB5.
    SMRi B1XGB5. Positions 1-337.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316385.ECDH10B_0473.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB01642 ; ACB01642 ; ECDH10B_0473 .
    GeneIDi 6059947.
    KEGGi ecd:ECDH10B_0473.
    PATRICi 18460722. VBIEscCol59506_0479.

    Phylogenomic databases

    eggNOGi COG2055.
    HOGENOMi HOG000173270.
    KOi K00073.
    OMAi MMVDVLS.
    OrthoDBi EOG6ZPSZJ.

    Enzyme and pathway databases

    BioCyci ECOL316385:GJ8B-463-MONOMER.

    Family and domain databases

    InterProi IPR003767. Malate/L-lactate_DH.
    IPR017590. Ureidoglycolate_dehydrogenase.
    [Graphical view ]
    PANTHERi PTHR11091. PTHR11091. 1 hit.
    Pfami PF02615. Ldh_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF89733. SSF89733. 1 hit.
    TIGRFAMsi TIGR03175. AllD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse."
      Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B., Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B., Posfai G., Weinstock G.M., Blattner F.R.
      J. Bacteriol. 190:2597-2606(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / DH10BImported.
    2. "Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization."
      Kim M.I., Shin I., Cho S., Lee J., Rhee S.
      PLoS ONE 7:e52066-e52066(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.77 ANGSTROMS) IN COMPLEX WITH NAD.

    Entry informationi

    Entry nameiB1XGB5_ECODH
    AccessioniPrimary (citable) accession number: B1XGB5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3