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B1XEJ9

- RPIA_ECODH

UniProt

B1XEJ9 - RPIA_ECODH

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Protein

Ribose-5-phosphate isomerase A

Gene

rpiA

Organism
Escherichia coli (strain K12 / DH10B)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.UniRule annotation

Catalytic activityi

D-ribose 5-phosphate = D-ribulose 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031Proton acceptorUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt, non-oxidative branch Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciECOL316385:GJ8B-2963-MONOMER.
UniPathwayiUPA00115; UER00412.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose-5-phosphate isomerase AUniRule annotation (EC:5.3.1.6UniRule annotation)
Alternative name(s):
Phosphoriboisomerase AUniRule annotation
Short name:
PRIUniRule annotation
Gene namesi
Name:rpiAUniRule annotation
Ordered Locus Names:ECDH10B_3089
OrganismiEscherichia coli (strain K12 / DH10B)
Taxonomic identifieri316385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001689: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Ribose-5-phosphate isomerase APRO_1000097661Add
BLAST

Proteomic databases

PRIDEiB1XEJ9.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi316385.ECDH10B_3089.

Structurei

3D structure databases

ProteinModelPortaliB1XEJ9.
SMRiB1XEJ9. Positions 2-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 314Substrate bindingUniRule annotation
Regioni81 – 844Substrate bindingUniRule annotation
Regioni94 – 974Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the ribose 5-phosphate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276368.
KOiK01807.
OMAiMDQLEMK.
OrthoDBiEOG67MF61.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.

Sequencei

Sequence statusi: Complete.

B1XEJ9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQDELKKAV GWAALQYVQP GTIVGVGTGS TAAHFIDALG TMKGQIEGAV
60 70 80 90 100
SSSDASTEKL KSLGIHVFDL NEVDSLGIYV DGADEINGHM QMIKGGGAAL
110 120 130 140 150
TREKIIASVA EKFICIADAS KQVDILGKFP LPVEVIPMAR SAVARQLVKL
160 170 180 190 200
GGRPEYRQGV VTDNGNVILD VHGMEILDPI AMENAINAIP GVVTVGLFAN
210
RGADVALIGT PDGVKTIVK
Length:219
Mass (Da):22,860
Last modified:May 20, 2008 - v1
Checksum:iB53C49CC3DB188BC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000948 Genomic DNA. Translation: ACB04015.1.
RefSeqiYP_001731793.1. NC_010473.1.

Genome annotation databases

EnsemblBacteriaiACB04015; ACB04015; ECDH10B_3089.
GeneIDi6060133.
KEGGiecd:ECDH10B_3089.
PATRICi18466085. VBIEscCol59506_3107.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000948 Genomic DNA. Translation: ACB04015.1 .
RefSeqi YP_001731793.1. NC_010473.1.

3D structure databases

ProteinModelPortali B1XEJ9.
SMRi B1XEJ9. Positions 2-219.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316385.ECDH10B_3089.

Proteomic databases

PRIDEi B1XEJ9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB04015 ; ACB04015 ; ECDH10B_3089 .
GeneIDi 6060133.
KEGGi ecd:ECDH10B_3089.
PATRICi 18466085. VBIEscCol59506_3107.

Phylogenomic databases

eggNOGi COG0120.
HOGENOMi HOG000276368.
KOi K01807.
OMAi MDQLEMK.
OrthoDBi EOG67MF61.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00412 .
BioCyci ECOL316385:GJ8B-2963-MONOMER.

Family and domain databases

HAMAPi MF_00170. Rib_5P_isom_A.
InterProi IPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view ]
PANTHERi PTHR11934. PTHR11934. 1 hit.
Pfami PF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00021. rpiA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse."
    Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B., Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B., Posfai G., Weinstock G.M., Blattner F.R.
    J. Bacteriol. 190:2597-2606(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / DH10B.

Entry informationi

Entry nameiRPIA_ECODH
AccessioniPrimary (citable) accession number: B1XEJ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: October 1, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3