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B1X5D6 (NU2C_PAUCH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NAD(P)H-quinone oxidoreductase subunit 2, organellar chromatophore
EC=1.6.5.-
Alternative name(s):
NAD(P)H dehydrogenase, subunit 2
NADH-plastoquinone oxidoreductase subunit 2
Gene names
Name:ndhB
Ordered Locus Names:PCC_0740
Encoded onPlastid; Organellar chromatophore
OrganismPaulinella chromatophora
Taxonomic identifier39717 [NCBI]
Taxonomic lineageEukaryota › Rhizaria › Cercozoa › Silicofilosea › Euglyphida › Paulinellidae › Paulinella

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration By similarity. HAMAP-Rule MF_00445

Catalytic activity

NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP-Rule MF_00445

Subunit structure

NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions By similarity.

Subcellular location

Plastid › organellar chromatophore thylakoid membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00445.

Sequence similarities

Belongs to the complex I subunit 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 512512NAD(P)H-quinone oxidoreductase subunit 2, organellar chromatophore HAMAP-Rule MF_00445
PRO_0000344284

Regions

Transmembrane6 – 2621Helical; Potential
Transmembrane43 – 6321Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane168 – 18821Helical; Potential
Transmembrane210 – 23021Helical; Potential
Transmembrane242 – 26221Helical; Potential
Transmembrane276 – 29621Helical; Potential
Transmembrane304 – 32421Helical; Potential
Transmembrane332 – 35221Helical; Potential
Transmembrane376 – 39621Helical; Potential
Transmembrane411 – 43121Helical; Potential
Transmembrane464 – 48421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
B1X5D6 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 8C927D63F7E8FFBD

FASTA51254,053
        10         20         30         40         50         60 
MENSGLLALP LNAATIVPEG AILLALLSSL LVDLAGEKTA SRWVPPICYA GLGSALILLA 

        70         80         90        100        110        120 
SQWNSTLSPS FLGAFLADNL AIAFRAIIAT STLFSLMISW RYVERSGAPM GEYAAILLAA 

       130        140        150        160        170        180 
TLGAMFLCGS TDLVSIFVSL ETLSVSSYLL AGYMKQDARS SEAALKYLLV GSATAAVFLY 

       190        200        210        220        230        240 
GASLLYGLTG GSTNLDAVAL ALQSSDTPVA ALALVFVLAT VAFKIAAVPF HQWTPDVYEG 

       250        260        270        280        290        300 
APTPIVAFLS VGSKTAGFAL ALRLLVGCFE SFDIQWKFLF SLLAILSMVL GNIVALSQTS 

       310        320        330        340        350        360 
MKRMLAYSSI GQAGFVMIGL VCGTEDGFAA MILYLATYLF MNMGAFACVI LFSIRTGSDL 

       370        380        390        400        410        420 
IADYAGLYQK DPLVTIGLSL CLLSLGGIPP MLGFFGKIYL FFAGWADHQY LLVVTGLITS 

       430        440        450        460        470        480 
VVSIYYYISV IRMMVVIEPK EASDVVKSYA AVNWNIPGLN PLRVALLVCV IVTGIGGIFS 

       490        500        510 
NPLFQWANSA VAGTPILQKV IVTALGTTGT IS

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References

[1]"Chromatophore genome sequence of Paulinella sheds light on acquisition of photosynthesis by eukaryotes."
Nowack E.C.M., Melkonian M., Gloeckner G.
Curr. Biol. 18:410-418(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000815 Genomic DNA. Translation: ACB43155.1.
RefSeqYP_002049365.1. NC_011087.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6481593.

Family and domain databases

HAMAPMF_00445. NDH1_NuoN_1.
InterProIPR010096. NADH-Q_OxRdtase_suN/2.
IPR001750. NADH_UbQ/plastoQ_OxRdtase.
[Graphical view]
PfamPF00361. Oxidored_q1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01770. NDH_I_N. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNU2C_PAUCH
AccessionPrimary (citable) accession number: B1X5D6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 20, 2008
Last modified: April 3, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

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