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B1X1N7

- B1X1N7_CYAA5

UniProt

B1X1N7 - B1X1N7_CYAA5

Protein

Alanine racemase

Gene

alr

Organism
Cyanothece sp. (strain ATCC 51142)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei59 – 591Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei158 – 1581SubstrateUniRule annotation
    Active sitei287 – 2871Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei335 – 3351Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCSP43989:GKC8-3763-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:cce_3719Imported
    OrganismiCyanothece sp. (strain ATCC 51142)Imported
    Taxonomic identifieri43989 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
    ProteomesiUP000001203: Chromosome circular

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei59 – 591N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi43989.cce_3719.

    Structurei

    3D structure databases

    ProteinModelPortaliB1X1N7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIYSHLAL.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1X1N7-1 [UniParc]FASTAAdd to Basket

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    MFSQESISGV ATKNRYNYHL SEIIRQRAWV EIDLSALSHN VVQIKQLLSP    50
    KTTLMAVVKA DAYGHGAIAV AQTVLQAGAK ALAVATLGEG IELREAGITA 100
    PILILGAINT PEEITAIAHW NLEPTLCYPE QALMVSDTLS QYEKPLSVHL 150
    KLDTGMSRLG TPWHQGTEFA SLVQQLPYLN LSSVYSHLAT ADDPDPSHMY 200
    LQHKRFKTAI DNLKAQGIVP PRLHFANSAA TLIAPQLHYD LVRVGLALYG 250
    LYPADHLRSI VPLKPVLQVK AKITQIKSIP ANTGVSYGYQ FVSDRPMKIA 300
    VVGIGYADGV PRNLSNRLQV LIHGQRACQI GAITMDQLML DVSHLRHVKV 350
    GDVVTLIGKD EDQEISADHW AKMLGTISWE ILCGFKHRLP RIKQLNKVEL 400
    GVVG 404
    Length:404
    Mass (Da):44,348
    Last modified:May 20, 2008 - v1
    Checksum:i2EA070C414682EC1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000806 Genomic DNA. Translation: ACB53067.1.
    RefSeqiYP_001805133.1. NC_010546.1.

    Genome annotation databases

    EnsemblBacteriaiACB53067; ACB53067; cce_3719.
    GeneIDi6170784.
    KEGGicyt:cce_3719.
    PATRICi21545816. VBICyaSp130209_3722.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000806 Genomic DNA. Translation: ACB53067.1 .
    RefSeqi YP_001805133.1. NC_010546.1.

    3D structure databases

    ProteinModelPortali B1X1N7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 43989.cce_3719.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB53067 ; ACB53067 ; cce_3719 .
    GeneIDi 6170784.
    KEGGi cyt:cce_3719.
    PATRICi 21545816. VBICyaSp130209_3722.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IYSHLAL.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci CSP43989:GKC8-3763-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51142Imported.

    Entry informationi

    Entry nameiB1X1N7_CYAA5
    AccessioniPrimary (citable) accession number: B1X1N7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3