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B1X1N7

- B1X1N7_CYAA5

UniProt

B1X1N7 - B1X1N7_CYAA5

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Protein
Alanine racemase
Gene
alr, cce_3719
Organism
Cyanothece sp. (strain ATCC 51142)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei59 – 591Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei158 – 1581Substrate By similarityUniRule annotation
Active sitei287 – 2871Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei335 – 3351Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciCSP43989:GKC8-3763-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:cce_3719Imported
OrganismiCyanothece sp. (strain ATCC 51142)Imported
Taxonomic identifieri43989 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000001203: Chromosome circular

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei59 – 591N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi43989.cce_3719.

Structurei

3D structure databases

ProteinModelPortaliB1X1N7.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiIYSHLAL.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1X1N7-1 [UniParc]FASTAAdd to Basket

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MFSQESISGV ATKNRYNYHL SEIIRQRAWV EIDLSALSHN VVQIKQLLSP    50
KTTLMAVVKA DAYGHGAIAV AQTVLQAGAK ALAVATLGEG IELREAGITA 100
PILILGAINT PEEITAIAHW NLEPTLCYPE QALMVSDTLS QYEKPLSVHL 150
KLDTGMSRLG TPWHQGTEFA SLVQQLPYLN LSSVYSHLAT ADDPDPSHMY 200
LQHKRFKTAI DNLKAQGIVP PRLHFANSAA TLIAPQLHYD LVRVGLALYG 250
LYPADHLRSI VPLKPVLQVK AKITQIKSIP ANTGVSYGYQ FVSDRPMKIA 300
VVGIGYADGV PRNLSNRLQV LIHGQRACQI GAITMDQLML DVSHLRHVKV 350
GDVVTLIGKD EDQEISADHW AKMLGTISWE ILCGFKHRLP RIKQLNKVEL 400
GVVG 404
Length:404
Mass (Da):44,348
Last modified:May 20, 2008 - v1
Checksum:i2EA070C414682EC1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000806 Genomic DNA. Translation: ACB53067.1.
RefSeqiYP_001805133.1. NC_010546.1.

Genome annotation databases

EnsemblBacteriaiACB53067; ACB53067; cce_3719.
GeneIDi6170784.
KEGGicyt:cce_3719.
PATRICi21545816. VBICyaSp130209_3722.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000806 Genomic DNA. Translation: ACB53067.1 .
RefSeqi YP_001805133.1. NC_010546.1.

3D structure databases

ProteinModelPortali B1X1N7.
ModBasei Search...

Protein-protein interaction databases

STRINGi 43989.cce_3719.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB53067 ; ACB53067 ; cce_3719 .
GeneIDi 6170784.
KEGGi cyt:cce_3719.
PATRICi 21545816. VBICyaSp130209_3722.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi IYSHLAL.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CSP43989:GKC8-3763-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51142Imported.

Entry informationi

Entry nameiB1X1N7_CYAA5
AccessioniPrimary (citable) accession number: B1X1N7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: July 9, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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