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B1X0N5 (SYR_CYAA5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:cce_3576
OrganismCyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]
Taxonomic identifier43989 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095357

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B1X0N5 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 6B988E91152DAC6E

FASTA58566,577
        10         20         30         40         50         60 
MTSINEQLTQ KFQDALVKSF GEEFKDVDPQ VNLARDLRHG DYQANIALPL AKKLGKNPRE 

        70         80         90        100        110        120 
IAQIIINNLS LNTICENPTI GGPGFINLKL KSSYLETQLK SLYQNQRLGI EKVHNADKVI 

       130        140        150        160        170        180 
VDFSSPNIAK EMHVGHLRST IIGDCIARTL EFLGYEVLRL NHVGDWGTQF GMLITYLKEV 

       190        200        210        220        230        240 
YPDALTQADV LEIGDLVNFY KQAKKRFDED PKFQEAAREA VVKLQSGDEE SRKAWQLLCD 

       250        260        270        280        290        300 
QSRREFQKIY DRLDVKLIER GESFYNPYLN DVIKALDEQG ILEKDQGAQC VFLEGFTNKS 

       310        320        330        340        350        360 
GDPLPLIVQK SDGGYNYATT DLAALKYRIQ EDKAKRIIYV TDAGQSNHFA QVFQVAKKAN 

       370        380        390        400        410        420 
FLPDTVDVTH VPFGLVKGED GKKLKTRSGE TVKLKDLLDE AVNYARKDLE NRLQAEDRKE 

       430        440        450        460        470        480 
SEDFINHVAE TVGISAVKYA DLSQNRISDY IFSYDKMLAL QGNTAPYMLY AYARIQSISR 

       490        500        510        520        530        540 
EGNIDYENLG ENIQILLKED TEIELGKYLL QLNETIKEVE KSLLPNRLCD YLYELSKKFN 

       550        560        570        580 
RFYENCPVLK SDEPVKTSRL LLCDLTARTL KLGLSLLGIS VLERM 

« Hide

References

[1]"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle."
Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B.
Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51142.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000806 Genomic DNA. Translation: ACB52924.1.
RefSeqYP_001804990.1. NC_010546.1.

3D structure databases

ProteinModelPortalB1X0N5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING43989.cce_3576.

Proteomic databases

PRIDEB1X0N5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB52924; ACB52924; cce_3576.
GeneID6170639.
KEGGcyt:cce_3576.
PATRIC21545530. VBICyaSp130209_3581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycCSP43989:GKC8-3618-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CYAA5
AccessionPrimary (citable) accession number: B1X0N5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries