B1X018 (PCYA_CYAA5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phycocyanobilin:ferredoxin oxidoreductase
EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	cce_3569

Organism

Cyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]

Taxonomic identifier

43989 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin By similarity. HAMAP MF_00618
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00618
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 246	246	Phycocyanobilin:ferredoxin oxidoreductase HAMAP MF_00618		PRO_1000190493

Sequences

	Sequence		Length	Mass (Da)
	B1X018 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: F9A737FEBAEAAB18	FASTA	246	28,088
	10 20 30 40 50 60 MTTVKTSPTT LPLHPLIHQL AEVIISHWQD YLDLSPYELP DGLGYVEGKL EGEKLVIENR 70 80 90 100 110 120 CYQSPQFRKM HLELAKVGQG LDILHCVMFP NPDYALPMFG CDIVAGKGGV SAAIADLSPA 130 140 150 160 170 180 NPELTLSNSY NQALSQLETP NFSDQRELPE WGDIFSEYCL FIRPHTPEEE KLFLKRVGDF 190 200 210 220 230 240 LKVHCQQANQ SQPGSTQQRE FNIQGQEYYC RKQQQNDKTR RVLEKAFGEA WANKYMTQVL FDIPNH

References

[1]

"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle." Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B. Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed: 18812508] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51142.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000806 Genomic DNA. Translation: ACB52917.1.
RefSeq	YP_001804983.1. NC_010546.1.
3D structure databases
ProteinModelPortal	B1X018.
SMR	B1X018. Positions 14-244.
ModBase	Search...
Protein-protein interaction databases
STRING	B1X018.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6170632.
GenomeReviews	Gene locus cce_3569 in contig CP000806_GR.
KEGG	cyt:cce_3569.
PATRIC	21545516. VBICyaSp130209_3574.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG561233.
OMA	NDKTRRV.
PhylomeDB	B1X018.
ProtClustDB	PRK02816.
Family and domain databases
HAMAP	MF_00618. Ferredoxin_bilin_red. [Tree]
InterPro	IPR009249. Ferredoxin-dep_bilin_Rdtase. IPR022870. Ferredoxin_bilin_OxRdtase. [Graphical view]
KO	K05371.
Pfam	PF05996. Fe_bilin_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCYA_CYAA5

Accession

Primary (citable) accession number: B1X018

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program