B1WZM8 (B1WZM8_CYAA5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthase EMBL ACB51180.1

Gene names

Name:	lpxB1 EMBL ACB51180.1
Ordered Locus Names:	cce_1830

Organism

Cyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]

Taxonomic identifier

43989 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1WZM8 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 411D5584077A0019	FASTA	385	43,506
	10 20 30 40 50 60 MQIFISTGEV SGDLQGSLLV EALYRQAKQQ NIPLDILALG GHLMEAAGAK LLGNTAGIGS 70 80 90 100 110 120 IGIVEALPFI IPTWLMQRRV KAYLRDNPPD VLILLDYMGP NVAFGKYARK YLPNVPIIYY 130 140 150 160 170 180 IAPQSWVWAP NNKTIEQFAE ITDILLAIFP EEARFFEKKG VNVKWVGHPL LDRMAKAPTR 190 200 210 220 230 240 EATRQALGLT EDQRVVALFP ASRYQELKHH LPLICKAAQK LQEKVPDVHF LLPISLKEYR 250 260 270 280 290 300 HTIEEMVKQY DLSITLFDGQ AMEVMAAADL AITKSGTVNL ELALLNVPQL VFFLVNPITI 310 320 330 340 350 360 WIARNILKFS VPFISPINLI VMKEIVPELL QEEATIDRIV DESLDLLLNP ERRQKTFADY 370 380 EEMRTLLGEI GVCDRVANEI LHYQK

References

[1]

"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle." Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B. Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed: 18812508] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000806 Genomic DNA. Translation: ACB51180.1.
RefSeq	YP_001803246.1. NC_010546.1.
3D structure databases
ProteinModelPortal	B1WZM8.
ModBase	Search...
Protein-protein interaction databases
STRING	B1WZM8.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6168879.
GenomeReviews	Gene locus cce_1830 in contig CP000806_GR.
KEGG	cyt:cce_1830.
PATRIC	21542115. VBICyaSp130209_1887.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	IGLANIM.
PhylomeDB	B1WZM8.
ProtClustDB	PRK00025.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1WZM8_CYAA5

Accession

Primary (citable) accession number: B1WZM8

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)