B1WXT3 (SURE_CYAA5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	cce_1570

Organism

Cyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]

Taxonomic identifier

43989 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	5'-nucleotidase surE HAMAP MF_00060		PRO_1000091998
Sites
	Metal binding	14	1	Divalent metal cation By similarity
	Metal binding	15	1	Divalent metal cation By similarity
	Metal binding	46	1	Divalent metal cation By similarity
	Metal binding	104	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1WXT3 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 2BE1AC7736E3E577	FASTA	276	30,444
	10 20 30 40 50 60 MTNPSTINIL ISNDDGIFAL GVRTLANTLA QAGYQVTVVC PDRERSATGH GLTLHRPIRA 70 80 90 100 110 120 DIVEDFFDPK ITAWSCSGTP SDCVKLALSS LIENRPDFIV SGINHGSNLG TDVLYSGTVS 130 140 150 160 170 180 AAMEGIIEGI PSIAMSLASF SSRQFQPGAD FACGLIQQLY DHPLPDSTLL NVNIPPVTAD 190 200 210 220 230 240 AIAGVMLTRQ GLRRYIENFE KRFDPRGKSY YWLAGELVTE IEQPDHIHLP SHIPTDVQAI 250 260 270 QHNYITLTPL QYNLTDVASF EYLQTNQWLE RSRDIK

References

[1]

"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle." Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B. Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed: 18812508] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51142.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000806 Genomic DNA. Translation: ACB50920.1.
RefSeq	YP_001802986.1. NC_010546.1.
3D structure databases
ProteinModelPortal	B1WXT3.
ModBase	Search...
Protein-protein interaction databases
STRING	B1WXT3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6168617.
GenomeReviews	Gene locus cce_1570 in contig CP000806_GR.
KEGG	cyt:cce_1570.
PATRIC	21541603. VBICyaSp130209_1632.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	SINVIYS.
PhylomeDB	B1WXT3.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_CYAA5

Accession

Primary (citable) accession number: B1WXT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program