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B1WXK9

- B1WXK9_CYAA5

UniProt

B1WXK9 - B1WXK9_CYAA5

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Protein

Isocitrate dehydrogenase [NADP]

Gene
icd, cce_3202
Organism
Cyanothece sp. (strain ATCC 51142)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciCSP43989:GKC8-3242-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:cce_3202Imported
OrganismiCyanothece sp. (strain ATCC 51142)Imported
Taxonomic identifieri43989 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000001203: Chromosome circular

Interactioni

Protein-protein interaction databases

STRINGi43989.cce_3202.

Structurei

3D structure databases

ProteinModelPortaliB1WXK9.
SMRiB1WXK9. Positions 31-495.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0538.
HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1WXK9-1 [UniParc]FASTAAdd to Basket

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MGELNRLGSV IKKQPLIIDH FMYEKLTPPT TGSKITFKDG KPIVPNDPIV    50
PFIRGDGTGV DIWPATEKVI DAAVKTAYGD SKKINWFKVY AGDEACDKYG 100
TYQYLPEDTL TAIREYGIAI KGPLTTPVGG GIRSLNVALR QIFELYACVR 150
PCRYYPGTPS PHKSPEKLDV IVYRENTEDI YLGIEWKEGT ELAQKLINYL 200
NNELIPATPE HGKKQIRLDS GIGVKPISKT GSQRLVRRAI EHALRLPKAK 250
QMVTLVHKGN IMKYTEGSFR DWGYELATSE FREVCVTERE SWILSNKEGN 300
ADISIEDNAR KVEPGYDGLT LDKKEEICGE VKGVLDAIWD SHGDGKWKDK 350
IMVNDRIADS IFQQIQTRPD EYSILATMNL NGDYLSDAAA AVVGGLGMGP 400
GANIGDTCAI FEATHGTAPK HAGLDRINPG SVILSGVMML EYMGWKEAAE 450
LIKKGIGNAI ANRQVTYDLA RLMEPKVDPP LKCSEFAQAI IDHFND 496
Length:496
Mass (Da):54,936
Last modified:May 20, 2008 - v1
Checksum:iAA93BA2BC59A0564
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000806 Genomic DNA. Translation: ACB52550.1.
RefSeqiWP_009547656.1. NC_010546.1.
YP_001804616.1. NC_010546.1.

Genome annotation databases

EnsemblBacteriaiACB52550; ACB52550; cce_3202.
GeneIDi6170263.
KEGGicyt:cce_3202.
PATRICi21544800. VBICyaSp130209_3218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000806 Genomic DNA. Translation: ACB52550.1 .
RefSeqi WP_009547656.1. NC_010546.1.
YP_001804616.1. NC_010546.1.

3D structure databases

ProteinModelPortali B1WXK9.
SMRi B1WXK9. Positions 31-495.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 43989.cce_3202.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB52550 ; ACB52550 ; cce_3202 .
GeneIDi 6170263.
KEGGi cyt:cce_3202.
PATRICi 21544800. VBICyaSp130209_3218.

Phylogenomic databases

eggNOGi COG0538.
HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci CSP43989:GKC8-3242-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 2 hits.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51142Imported.

Entry informationi

Entry nameiB1WXK9_CYAA5
AccessioniPrimary (citable) accession number: B1WXK9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: September 3, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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