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B1WXK9

- B1WXK9_CYAA5

UniProt

B1WXK9 - B1WXK9_CYAA5

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Cyanothece sp. (strain ATCC 51142)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciCSP43989:GKC8-3242-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:cce_3202Imported
    OrganismiCyanothece sp. (strain ATCC 51142)Imported
    Taxonomic identifieri43989 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
    ProteomesiUP000001203: Chromosome circular

    Interactioni

    Protein-protein interaction databases

    STRINGi43989.cce_3202.

    Structurei

    3D structure databases

    ProteinModelPortaliB1WXK9.
    SMRiB1WXK9. Positions 31-495.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 2 hits.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1WXK9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGELNRLGSV IKKQPLIIDH FMYEKLTPPT TGSKITFKDG KPIVPNDPIV    50
    PFIRGDGTGV DIWPATEKVI DAAVKTAYGD SKKINWFKVY AGDEACDKYG 100
    TYQYLPEDTL TAIREYGIAI KGPLTTPVGG GIRSLNVALR QIFELYACVR 150
    PCRYYPGTPS PHKSPEKLDV IVYRENTEDI YLGIEWKEGT ELAQKLINYL 200
    NNELIPATPE HGKKQIRLDS GIGVKPISKT GSQRLVRRAI EHALRLPKAK 250
    QMVTLVHKGN IMKYTEGSFR DWGYELATSE FREVCVTERE SWILSNKEGN 300
    ADISIEDNAR KVEPGYDGLT LDKKEEICGE VKGVLDAIWD SHGDGKWKDK 350
    IMVNDRIADS IFQQIQTRPD EYSILATMNL NGDYLSDAAA AVVGGLGMGP 400
    GANIGDTCAI FEATHGTAPK HAGLDRINPG SVILSGVMML EYMGWKEAAE 450
    LIKKGIGNAI ANRQVTYDLA RLMEPKVDPP LKCSEFAQAI IDHFND 496
    Length:496
    Mass (Da):54,936
    Last modified:May 20, 2008 - v1
    Checksum:iAA93BA2BC59A0564
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000806 Genomic DNA. Translation: ACB52550.1.
    RefSeqiWP_009547656.1. NC_010546.1.
    YP_001804616.1. NC_010546.1.

    Genome annotation databases

    EnsemblBacteriaiACB52550; ACB52550; cce_3202.
    GeneIDi6170263.
    KEGGicyt:cce_3202.
    PATRICi21544800. VBICyaSp130209_3218.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000806 Genomic DNA. Translation: ACB52550.1 .
    RefSeqi WP_009547656.1. NC_010546.1.
    YP_001804616.1. NC_010546.1.

    3D structure databases

    ProteinModelPortali B1WXK9.
    SMRi B1WXK9. Positions 31-495.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 43989.cce_3202.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB52550 ; ACB52550 ; cce_3202 .
    GeneIDi 6170263.
    KEGGi cyt:cce_3202.
    PATRICi 21544800. VBICyaSp130209_3218.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci CSP43989:GKC8-3242-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 2 hits.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51142Imported.

    Entry informationi

    Entry nameiB1WXK9_CYAA5
    AccessioniPrimary (citable) accession number: B1WXK9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3