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B1WTP5 (B1WTP5_CYAA5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF2 HAMAP MF_01840
Ordered Locus Names:cce_4412
OrganismCyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]
Taxonomic identifier43989 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B1WTP5 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: F13E64FD1F0E5C0B

FASTA35942,349
        10         20         30         40         50         60 
MVMVKTPVKP DQPKPGTKAP SQETLLTPRF YITDFETAAN LSLTEQETEL NAMLTEMRND 

        70         80         90        100        110        120 
YNRHHFVRNE EFKTGNWDHL DETTREGFIE YLERSCISEF SGFLLFKELS RKLKGRNPIL 

       130        140        150        160        170        180 
SEMFHLMARD EARHAGFLNK AMADFNLSLD LGKVTKTRTY TFFPLEWVIY TVYLSEKIGY 

       190        200        210        220        230        240 
WRYIIIFHHL EKHPEKQFYP IFKKFENWCQ DENRHGDIFT ALLRSQPKLW KTWKARLWSR 

       250        260        270        280        290        300 
FFLLSVFATH TLTVHERASF YESLGLNATE FDKEVIRKTN ETSARAFPSV LDVDHPEFYP 

       310        320        330        340        350 
RLQRCSQRNL KMKEIGESKA PKFVKTLRKL PLMAGIVGDL LRIYLIKPID AEALRGTVR

« Hide

References

[1]"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle."
Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B.
Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed: 18812508] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000806 Genomic DNA. Translation: ACB53760.1.
RefSeqYP_001805826.1. NC_010546.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB1WTP5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6171490.
GenomeReviewsGene locus cce_4412 in contig CP000806_GR.
KEGGcyt:cce_4412.
PATRIC21547158. VBICyaSp130209_4383.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMANRHGDIF.
PhylomeDBB1WTP5.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1WTP5_CYAA5
AccessionPrimary (citable) accession number: B1WTP5
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info