ID   B1WRT2_CROS5            Unreviewed;       606 AA.
AC   B1WRT2;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=cce_4175 {ECO:0000313|EMBL:ACB53523.1};
OS   Crocosphaera subtropica (strain ATCC 51142 / BH68) (Cyanothece sp. (strain
OS   ATCC 51142)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Crocosphaera; Crocosphaera subtropica.
OX   NCBI_TaxID=43989 {ECO:0000313|EMBL:ACB53523.1, ECO:0000313|Proteomes:UP000001203};
RN   [1] {ECO:0000313|EMBL:ACB53523.1, ECO:0000313|Proteomes:UP000001203}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51142 / BH68 {ECO:0000313|Proteomes:UP000001203};
RX   PubMed=18812508; DOI=10.1073/pnas.0805418105;
RA   Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C.,
RA   Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K.,
RA   Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B.;
RT   "The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium
RT   important in the marine nitrogen cycle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008).
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DR   EMBL; CP000806; ACB53523.1; -; Genomic_DNA.
DR   RefSeq; WP_009543748.1; NC_010546.1.
DR   AlphaFoldDB; B1WRT2; -.
DR   STRING; 43989.cce_4175; -.
DR   KEGG; cyt:cce_4175; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 415644at2; -.
DR   Proteomes; UP000001203; Chromosome circular.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001203}.
FT   DOMAIN          32..92
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          209..342
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          349..603
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   606 AA;  69485 MW;  1C6E61C59A65B58D CRC64;
     MNDTKKNTNH RYILVLEDSN SRRTISLEKS KYSLGRHSSN SIIIYSKQVS RQHATLIRKF
     NRKTNQDAFW ILDGDLDGKK SQNGIFVNGE KCTIHELKDG DLINFGCEVN GSYHTIFPAQ
     ISESFIDKQI SKKIEQSAPQ AINQAPTLYL GNPNQQSTYI LQSPSLNDLG NDDTFPEESY
     LDPVTELPNR ILFNEYISIA VTNAKRHNHC LAVLLIDIEH FSQINDKFGY RIGDYFLQVI
     AQRLKNCIRT GDIVSRWGGD EFAILLPHIK EADNLYKITQ RIIKELKSPF IVEENTQVLV
     TYLGIATYPK NGQVPQELLN YAETQLINHK KTGNHNLLPE NLNQTNPPLS QIEKRLYEAL
     TKEELCLYYQ PQFNTNAKKI EAMEAFIRWK HPKYGLIPPQ QFLPWAEKTE LVVPLTRWIL
     EKACTHNKIW QMNKLSSVVV SVNLSIAQFH HPQLVDLIDE VLTSTGLDPQ WLELEITESI
     ILKDIKLAYE VSRELKKLGV RVCLDDFGIG YAAVNHLHQM PFDTIKIDVS LIKNIKENPE
     NTTLIAALIF LGNSFEMRVV AEGVETEQQL NTLHHLHCQI MQGYYFSKPL SVEKATQFLT
     FDYGQS
//