B1WQY5 (B1WQY5_CYAA5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor G 2 HAMAP MF_00054
Short name=EF-G 2 HAMAP MF_00054

Gene names

Name:	fus1 EMBL ACB53437.1
Synonyms:	fusA2 HAMAP MF_00054
Ordered Locus Names:	cce_4089

Organism

Cyanothece sp. (strain ATCC 51142) [Complete proteome] [HAMAP]

Taxonomic identifier

43989 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	697 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome By similarity. HAMAP MF_00054
Subcellular location	Cytoplasm By similarity HAMAP MF_00054.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. HAMAP MF_00054

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP MF_00054
Ligand	GTP-binding RuleBase RU000323 HAMAP MF_00054 Nucleotide-binding
Molecular function	Elongation factor HAMAP MF_00054 EMBL ACB53437.1
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	17 – 24	8	GTP By similarity HAMAP MF_00054
	Nucleotide binding	81 – 85	5	GTP By similarity HAMAP MF_00054
	Nucleotide binding	135 – 138	4	GTP By similarity HAMAP MF_00054

Sequences

	Sequence		Length	Mass (Da)
	B1WQY5 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: C74A2836D2A96F38	FASTA	697	77,221
	10 20 30 40 50 60 MARNIPLERV RNIGIAAHID AGKTTTTERI LFYTGIAYKL GEVHEGTATM DWMAQEQERG 70 80 90 100 110 120 ITITAAAIST SWLDHRINII DTPGHVDFTI EVERSMRVLD GVIAVFCSVG GVQPQSETVW 130 140 150 160 170 180 RQANRYHVPR IAFVNKMDRT GANFFKVYQQ IRDRLKANAV PIQIPIGTES EFRGIVDLVR 190 200 210 220 230 240 MRAKIYQDDL GKNIEDTEIP DEYLEQAQEY RAKLIEAIAE IDETLLEKYL EGEQLTEEDI 250 260 270 280 290 300 RQGLRKGTLN KTIIPMLCGS AFKNKGVQLL LDAVVDYLPS PLDVPPITGL LKDGTEDSRK 310 320 330 340 350 360 ADDQEPFSAL AFKIASDPYG RLTFMRVYSG VLEKGNYVYN ATQEQKERIS RLIVLKSNDR 370 380 390 400 410 420 IEVDELRAGD LGAAIGLRNT ITGDTLCDEK HPILLESLYI PEPVISVAVE PKTKQDMEKL 430 440 450 460 470 480 SKALQALSDE DPTFKVSVDP ETNQTVIAGM GELHLEILVD RMLREYKVEA TVGQPQVAYR 490 500 510 520 530 540 ETIRKPSDAE GKYIRQSGGK GQYGHVVIEL EPGEAGSGFE FVSKIVGGTI PKEFISPAEQ 550 560 570 580 590 600 GMKEACDSGI IAGYPLIDVK VTLVDGSFHD VDSSEMAFKI AGSMAIRNAV KKASPVLLEP 610 620 630 640 650 660 MMKVEVEVPE DFLGDVIGDL NARRGQIEGM NTDDGLAKIS ADVPLAEMFG YATDIRSKTQ 670 680 690 GRGIFSMEFS HYAEVPRNVA EAIVLKNTGN AYTYDSE

References

[1]

"The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle." Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C., Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K., Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B. Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008) [PubMed: 18812508] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000806 Genomic DNA. Translation: ACB53437.1.
RefSeq	YP_001805503.1. NC_010546.1.
3D structure databases
ProteinModelPortal	B1WQY5.
SMR	B1WQY5. Positions 7-684.
ModBase	Search...
Protein-protein interaction databases
STRING	B1WQY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6171165.
GenomeReviews	Gene locus cce_4089 in contig CP000806_GR.
KEGG	cyt:cce_4089.
PATRIC	21546536. VBICyaSp130209_4073.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG737692.
OMA	MAFKEAS.
PhylomeDB	B1WQY5.
ProtClustDB	PRK00007.
Family and domain databases
HAMAP	MF_00054_B. EF_G_EF_2_B. [Tree]
InterPro	IPR009022. Elongation_fac_G/III/V. IPR000795. ProtSyn_GTP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR005225. Small_GTP-bd_dom. IPR004540. Transl_elong_EFG/EF2. IPR000640. Transl_elong_EFG/EF2_C. IPR005517. Transl_elong_EFG/EF2_IV. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.30.70.240. Transl_elong_EFG/EF2_C. 1 hit.
KO	K02355.
Pfam	PF00679. EFG_C. 1 hit. PF03764. EFG_IV. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SMART	SM00838. EFG_C. 1 hit. SM00889. EFG_IV. 1 hit. [Graphical view]
SUPFAM	SSF54980. EFG_III_V. 2 hits. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00484. EF-G. 1 hit. TIGR00231. Small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1WQY5_CYAA5

Accession

Primary (citable) accession number: B1WQY5

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)