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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cyanothece sp. (strain ATCC 51142)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei197 – 1971UniRule annotation
Active sitei667 – 6671UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCSP43989:GKC8-3872-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:cce_3822Imported
OrganismiCyanothece sp. (strain ATCC 51142)Imported
Taxonomic identifieri43989 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000001203 Componenti: Chromosome circular

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi43989.cce_3822.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1WNZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLVMLLESL QSTVEEVNIF STSDLFLRQR LKLVESLWES VLKAECGQEL
60 70 80 90 100
VDLLEKLRKI CSPEGQVTDK PKTSINELIE GLELNEAIRA ARAFALYFQL
110 120 130 140 150
INIVEQHYEQ RDQQLNRRAT YQESEKARNN HAKEENKANG SVGADLLEKA
160 170 180 190 200
LVGGTENQEK GGTFHWLFPQ LKRLNVPPQQ IQRLLEQLDI RLVFTAHPTE
210 220 230 240 250
IVRHTIRLKQ RRIATLLRRL DYAEESFRGM GLSSSWEAES IIEQLNEEIR
260 270 280 290 300
LWWRTDELHQ FKPSVLDEVD YTLHYFDEVL CDALPQLSQR LQQALKANFP
310 320 330 340 350
RIKPPHNTFC RFGSWVGGDR DGNPFVTPEV TWRTACYQRN LILEKYLAAI
360 370 380 390 400
EDLTEILSSS LHWSNVSQDL LDSLERDRVA MPEIYDELAI RYRQEPYRLK
410 420 430 440 450
LAYIEKRLET TRDRNNHLAN PEKRQILTEE TPPNIYHSGE EFEAELQLIK
460 470 480 490 500
RNLEETGLKC QALENLIFQA QMFGFTLTQL DFRQESSRHS ETIEVIANYL
510 520 530 540 550
NVLPRPYGEL SETEKVNWLV GELQTRRPLI PMEMPFDEKT IETIETMRML
560 570 580 590 600
RYLQQEFGVE ICQTYIISMT NDVSDVLEVL LLAKEAGLYD PGTSTTTIRI
610 620 630 640 650
VPLFETVDDL KRAPEIMDAL FKLTLYRAAL AGGYDYLDEA KKEQLPPPEL
660 670 680 690 700
QPANLQEIMV GYSDSNKDSG FLSSNWEIHK AQKSLQKVAE PYGLALRLFH
710 720 730 740 750
GRGGSVGRGG GPAYAAILAQ PTGTINGRIK ITEQGEVLAS KYSLPELALY
760 770 780 790 800
NLETATTAVI QASLLGSGFD DIVPWNDIME ELASSARKAY RSLIYEQPDF
810 820 830 840 850
LDFFLSVTPI PEISQLQISS RPARRKSGKK DLSTLRAIPW VFSWTQSRFL
860 870 880 890 900
LPAWYGVGTA LESFLQQEPN ENLKLLRYFY LKWPFFKMVI SKVEMTLSKV
910 920 930 940 950
DLQIAHHYVK ELSQPEDIER FNKVFERISQ EYHRTRDIIL SINEQPKLLE
960 970 980 990 1000
GDAGLQRSVQ LRNGTIVPLG FLQVSLLKRL RQYTRQAESG VIHFRYSKEE
1010 1020
LLRGALLTIN GIAAGMRNTG
Length:1,020
Mass (Da):117,283
Last modified:May 20, 2008 - v1
Checksum:i3BAACD5E8385A87C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000806 Genomic DNA. Translation: ACB53170.1.
RefSeqiWP_012362273.1. NC_010546.1.
YP_001805236.1. NC_010546.1.

Genome annotation databases

EnsemblBacteriaiACB53170; ACB53170; cce_3822.
KEGGicyt:cce_3822.
PATRICi21546028. VBICyaSp130209_3823.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000806 Genomic DNA. Translation: ACB53170.1.
RefSeqiWP_012362273.1. NC_010546.1.
YP_001805236.1. NC_010546.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi43989.cce_3822.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB53170; ACB53170; cce_3822.
KEGGicyt:cce_3822.
PATRICi21546028. VBICyaSp130209_3823.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciCSP43989:GKC8-3872-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51142Imported.

Entry informationi

Entry nameiB1WNZ1_CYAA5
AccessioniPrimary (citable) accession number: B1WNZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: April 29, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.