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UniProtKB - B1WC97 (KCTD7_RAT)

UniProt

B1WC97 - KCTD7_RAT

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Protein

BTB/POZ domain-containing protein KCTD7

Gene

Kctd7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the control of excitability of cortical neurons.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
BTB/POZ domain-containing protein KCTD7
Gene namesi
Name:Kctd7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1582914. Kctd7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289BTB/POZ domain-containing protein KCTD7PRO_0000369240Add
BLAST

Proteomic databases

PaxDbiB1WC97.
PRIDEiB1WC97.

Expressioni

Gene expression databases

BgeeiENSRNOG00000042384.

Interactioni

Subunit structurei

Interacts with CUL3.By similarity

Structurei

3D structure databases

ProteinModelPortaliB1WC97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 14189BTBAdd
BLAST

Sequence similaritiesi

Contains 1 BTB (POZ) domain.Curated

Phylogenomic databases

eggNOGiKOG2723. Eukaryota.
ENOG410Z155. LUCA.
GeneTreeiENSGT00530000063071.
HOGENOMiHOG000113201.
InParanoidiB1WC97.
OMAiHREAQYY.
OrthoDBiEOG091G0X03.
PhylomeDBiB1WC97.
TreeFamiTF315332.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
[Graphical view]
PfamiPF02214. BTB_2. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

B1WC97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVVNGREPD SRHSDGAMSS SEAEDDFLEP ATPTATQAGH GLPLLPQEFP 
        60         70         80         90        100
EVVPLNIGGA HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD SEGRYFIDRD 
       110        120        130        140        150
GTHFGDVLNF LRSGDLPPRE HVRAVHKEAQ YYAIGPLLEQ LENMQPLKGE 
       160        170        180        190        200
KVRQAFLGLM PYYKDHLERI VEIARLRAVQ RKARFAKLKV CVFKEEMPIT 
       210        220        230        240        250
PYECPLLNSL RFERSESDGQ LFEHHCEVDV SFGPWEAVAD VYDLLHCLVT 
       260        270        280 
DLSAQGLTVD HQCIGVCDKH LVNHYYCKRP IYEFKITWW
Length:289
Mass (Da):33,093
Last modified:May 20, 2008 - v1
Checksum:i6DA58790AB84B5FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473973 Genomic DNA. Translation: EDM13466.1.
BC162055 mRNA. Translation: AAI62055.1.
RefSeqiNP_001121666.1. NM_001128194.2.
UniGeneiRn.103510.

Genome annotation databases

EnsembliENSRNOT00000001198; ENSRNOP00000001198; ENSRNOG00000042384.
GeneIDi688993.
KEGGirno:688993.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473973 Genomic DNA. Translation: EDM13466.1.
BC162055 mRNA. Translation: AAI62055.1.
RefSeqiNP_001121666.1. NM_001128194.2.
UniGeneiRn.103510.

3D structure databases

ProteinModelPortaliB1WC97.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiB1WC97.
PRIDEiB1WC97.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000001198; ENSRNOP00000001198; ENSRNOG00000042384.
GeneIDi688993.
KEGGirno:688993.

Organism-specific databases

CTDi154881.
RGDi1582914. Kctd7.

Phylogenomic databases

eggNOGiKOG2723. Eukaryota.
ENOG410Z155. LUCA.
GeneTreeiENSGT00530000063071.
HOGENOMiHOG000113201.
InParanoidiB1WC97.
OMAiHREAQYY.
OrthoDBiEOG091G0X03.
PhylomeDBiB1WC97.
TreeFamiTF315332.

Miscellaneous databases

PROiB1WC97.

Gene expression databases

BgeeiENSRNOG00000042384.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
[Graphical view]
PfamiPF02214. BTB_2. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKCTD7_RAT
AccessioniPrimary (citable) accession number: B1WC97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.