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Protein

BTB/POZ domain-containing protein KCTD7

Gene

Kctd7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the control of excitability of cortical neurons.By similarity

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-8951664 Neddylation
R-RNO-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Recommended name:
BTB/POZ domain-containing protein KCTD7
Gene namesi
Name:Kctd7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1582914 Kctd7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003692401 – 289BTB/POZ domain-containing protein KCTD7Add BLAST289

Proteomic databases

PaxDbiB1WC97
PRIDEiB1WC97

Expressioni

Gene expression databases

BgeeiENSRNOG00000042384

Interactioni

Subunit structurei

Interacts with CUL3.By similarity

Structurei

3D structure databases

ProteinModelPortaliB1WC97
SMRiB1WC97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 141BTBAdd BLAST89

Phylogenomic databases

eggNOGiKOG2723 Eukaryota
ENOG410Z155 LUCA
GeneTreeiENSGT00920000149007
HOGENOMiHOG000113201
InParanoidiB1WC97
KOiK21917
OMAiHREAQYY
OrthoDBiEOG091G0X03
PhylomeDBiB1WC97
TreeFamiTF315332

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

B1WC97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVVNGREPD SRHSDGAMSS SEAEDDFLEP ATPTATQAGH GLPLLPQEFP
60 70 80 90 100
EVVPLNIGGA HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD SEGRYFIDRD
110 120 130 140 150
GTHFGDVLNF LRSGDLPPRE HVRAVHKEAQ YYAIGPLLEQ LENMQPLKGE
160 170 180 190 200
KVRQAFLGLM PYYKDHLERI VEIARLRAVQ RKARFAKLKV CVFKEEMPIT
210 220 230 240 250
PYECPLLNSL RFERSESDGQ LFEHHCEVDV SFGPWEAVAD VYDLLHCLVT
260 270 280
DLSAQGLTVD HQCIGVCDKH LVNHYYCKRP IYEFKITWW
Length:289
Mass (Da):33,093
Last modified:May 20, 2008 - v1
Checksum:i6DA58790AB84B5FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473973 Genomic DNA Translation: EDM13466.1
BC162055 mRNA Translation: AAI62055.1
RefSeqiNP_001121666.1, NM_001128194.2
UniGeneiRn.103510

Genome annotation databases

EnsembliENSRNOT00000001198; ENSRNOP00000001198; ENSRNOG00000042384
GeneIDi688993
KEGGirno:688993

Similar proteinsi

Entry informationi

Entry nameiKCTD7_RAT
AccessioniPrimary (citable) accession number: B1WC97
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: June 20, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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