UniProtKB - B1WC97 (KCTD7_RAT)
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Protein
BTB/POZ domain-containing protein KCTD7
Gene
Kctd7
Organism
Rattus norvegicus (Rat)
Status
Functioni
May be involved in the control of excitability of cortical neurons.By similarity
GO - Biological processi
- cellular potassium ion homeostasis Source: Ensembl
- glutamate homeostasis Source: RGD
- membrane hyperpolarization Source: Ensembl
- positive regulation of transporter activity Source: Ensembl
- protein homooligomerization Source: InterPro
Enzyme and pathway databases
Reactomei | R-RNO-8951664. Neddylation. R-RNO-983168. Antigen processing: Ubiquitination & Proteasome degradation. |
Names & Taxonomyi
Protein namesi | Recommended name: BTB/POZ domain-containing protein KCTD7 |
Gene namesi | Name:Kctd7 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1582914. Kctd7. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000369240 | 1 – 289 | BTB/POZ domain-containing protein KCTD7Add BLAST | 289 |
Proteomic databases
PaxDbi | B1WC97. |
PRIDEi | B1WC97. |
Interactioni
Subunit structurei
Interacts with CUL3.By similarity
Structurei
3D structure databases
ProteinModelPortali | B1WC97. |
SMRi | B1WC97. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 53 – 141 | BTBAdd BLAST | 89 |
Phylogenomic databases
eggNOGi | KOG2723. Eukaryota. ENOG410Z155. LUCA. |
GeneTreei | ENSGT00760000119013. |
HOGENOMi | HOG000113201. |
InParanoidi | B1WC97. |
KOi | K21917. |
OMAi | HREAQYY. |
OrthoDBi | EOG091G0X03. |
PhylomeDBi | B1WC97. |
TreeFami | TF315332. |
Family and domain databases
InterProi | View protein in InterPro IPR000210. BTB/POZ_dom. IPR011333. SKP1/BTB/POZ_sf. IPR003131. T1-type_BTB. |
Pfami | View protein in Pfam PF02214. BTB_2. 1 hit. |
SMARTi | View protein in SMART SM00225. BTB. 1 hit. |
SUPFAMi | SSF54695. SSF54695. 1 hit. |
i Sequence
Sequence statusi: Complete.
B1WC97-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVVVNGREPD SRHSDGAMSS SEAEDDFLEP ATPTATQAGH GLPLLPQEFP
60 70 80 90 100
EVVPLNIGGA HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD SEGRYFIDRD
110 120 130 140 150
GTHFGDVLNF LRSGDLPPRE HVRAVHKEAQ YYAIGPLLEQ LENMQPLKGE
160 170 180 190 200
KVRQAFLGLM PYYKDHLERI VEIARLRAVQ RKARFAKLKV CVFKEEMPIT
210 220 230 240 250
PYECPLLNSL RFERSESDGQ LFEHHCEVDV SFGPWEAVAD VYDLLHCLVT
260 270 280
DLSAQGLTVD HQCIGVCDKH LVNHYYCKRP IYEFKITWW
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473973 Genomic DNA. Translation: EDM13466.1. BC162055 mRNA. Translation: AAI62055.1. |
RefSeqi | NP_001121666.1. NM_001128194.2. |
UniGenei | Rn.103510. |
Genome annotation databases
Ensembli | ENSRNOT00000001198; ENSRNOP00000001198; ENSRNOG00000042384. |
GeneIDi | 688993. |
KEGGi | rno:688993. |
Similar proteinsi
Entry informationi
Entry namei | KCTD7_RAT | |
Accessioni | B1WC97Primary (citable) accession number: B1WC97 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 14, 2009 |
Last sequence update: | May 20, 2008 | |
Last modified: | February 28, 2018 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |