B1WC34 (B1WC34_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Prkcsh Ensembl ENSRNOP00000018009

Submitted name:
Protein kinase C substrate 80K-H EMBL AAI61987.1
Submitted name:
Protein kinase C substrate 80K-H (Predicted), isoform CRA_b EMBL EDL78243.1

Gene names

Name:	Prkcsh EMBL AAI61987.1 Ensembl ENSRNOP00000018009 RGD 1309628
Synonyms:	Prkcsh_predicted EMBL EDL78243.1
ORF Names:	rCG_31596 EMBL EDL78243.1

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	Calcium RuleBase RU000331
Molecular function	Kinase EMBL AAI61987.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	N-glycan processing Inferred from electronic annotation. Source: InterPro negative regulation of neuron projection development Inferred from electronic annotation. Source: Compara protein heterooligomerization Inferred from physical interaction PubMed 15707389. Source: RGD
Cellular_component	plasma membrane Traceable author statement. Source: Reactome
Molecular_function	RNA binding Inferred from electronic annotation. Source: Compara calcium ion binding Inferred from electronic annotation. Source: InterPro kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1WC34 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: C9C1089E36012BE8	FASTA	525	59,218
	10 20 30 40 50 60 MLLLLLLLPL CWAVEVKRPR GVSLSNHHFY DESKPFTCLD GTATIPFDQV NDDYCDCKDG 70 80 90 100 110 120 SDEPGTAACP NGSFHCTNTG YKPLYILSSR VNDGVCDCCD GTDEYNSGTV CENTCREKGR 130 140 150 160 170 180 KEKESLQQLA EVTREGFRLK KILIEEWKTA REEKQSKLLE LQAGKKSLED QVETLRTAKE 190 200 210 220 230 240 EAERPEKEAK DQHRKLWEEQ QAAAKARREQ ELAASAFQEL DDNMDGLVSL AELQTHPELD 250 260 270 280 290 300 TDGDGGLSEE EAQALLSGDT QTDTTSFYDR VWAAIRDKYR SEVPPTDIPV PEVTEPKEEK 310 320 330 340 350 360 LPVLPPMEEE EEEEEPEEEE EEEEEEVPGE QPKEVPPPQQ PLRPPSPAED EKMPPYDEET 370 380 390 400 410 420 QAIIDAAQEA RNKFEEVERS LKEMEESIRS LEQEISFDFG PSGEFAYLYS QCYELTTNEY 430 440 450 460 470 480 VYRLCPFKLV SQKPKHGGSP TSLGTWGSWA GPDDDKFSAM KYEQGTGCWQ GPNRSTTVRL 490 500 510 520 LCGKETVVTS TTEPSRCEYL MELMTPAACP EPPPEVPTDG DHDEL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung EMBL AAI61987.1.
[2]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000018009.
[3]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL78243.1.
[4]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL78243.1.
[5]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000018009.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06053688 Genomic DNA. No translation available. BC161987 mRNA. Translation: AAI61987.1. CH473993 Genomic DNA. Translation: EDL78243.1.
IPI	IPI00388209.
RefSeq	NP_001100276.1. NM_001106806.2.
UniGene	Rn.104417.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000018009.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000018009; ENSRNOP00000018009; ENSRNOG00000013360.
GeneID	300445.
KEGG	rno:300445.
UCSC	RGD:1309628. rat.
Organism-specific databases
CTD	5589.
RGD	1309628. Prkcsh.
Phylogenomic databases
eggNOG	NOG289998.
GeneTree	ENSGT00510000047770.
HOGENOM	HOG000007805.
HOVERGEN	HBG051738.
KO	K08288.
OMA	GPEENKF.
OrthoDB	EOG4DFPNG.
Gene expression databases
Genevestigator	B1WC34.
Family and domain databases
Gene3D	4.10.400.10. 1 hit.
InterPro	IPR018247. EF_Hand_1_Ca_BS. IPR002048. EF_hand_dom. IPR026874. Glucosidase_2_bsu. IPR002172. LDrepeatLR_classA_rpt. IPR009011. Man6P_isomerase_rcpt-bd_dom. [Graphical view]
PANTHER	PTHR12630:SF1. PTHR12630:SF1. 1 hit.
Pfam	PF13202. EF_hand_3. 2 hits. [Graphical view]
SMART	SM00192. LDLa. 1 hit. [Graphical view]
SUPFAM	SSF50911. Man6php_recept. 1 hit.
PROSITE	PS00018. EF_HAND_1. 1 hit. PS50222. EF_HAND_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChEMBL	CHEMBL2779.
NextBio	646903.

Entry information

Entry name

B1WC34_RAT

Accession

Primary (citable) accession number: B1WC34

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)