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B1WC34

- B1WC34_RAT

UniProt

B1WC34 - B1WC34_RAT

Protein
Submitted name:

Protein Prkcsh

Gene

Prkcsh

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. kinase activity Source: UniProtKB-KW
    3. RNA binding Source: Ensembl

    GO - Biological processi

    1. in utero embryonic development Source: Ensembl
    2. liver development Source: Ensembl
    3. negative regulation of neuron projection development Source: Ensembl
    4. N-glycan processing Source: InterPro
    5. nitrogen compound metabolic process Source: Ensembl
    6. protein heterooligomerization Source: RGD
    7. renal system development Source: Ensembl

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Keywords - Ligandi

    CalciumUniRule annotation

    Enzyme and pathway databases

    ReactomeiREACT_196231. Advanced glycosylation endproduct receptor signaling.
    REACT_196411. N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
    REACT_196415. Calnexin/calreticulin cycle.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein PrkcshImported
    Submitted name:
    Protein kinase C substrate 80K-HImported
    Submitted name:
    Protein kinase C substrate 80K-H (Predicted), isoform CRA_bImported
    Gene namesi
    Name:PrkcshImported
    Synonyms:Prkcsh_predictedImported
    ORF Names:rCG_31596Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 8

    Organism-specific databases

    RGDi1309628. Prkcsh.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: Reactome

    Expressioni

    Gene expression databases

    GenevestigatoriB1WC34.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000018009.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG289998.
    GeneTreeiENSGT00510000047770.
    HOGENOMiHOG000007805.
    HOVERGENiHBG051738.
    KOiK08288.
    OMAiDHKEQID.
    OrthoDBiEOG7DZ8JX.
    TreeFamiTF329550.

    Family and domain databases

    Gene3Di2.70.130.10. 2 hits.
    4.10.400.10. 1 hit.
    InterProiIPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR026874. Glucosidase_2_bsu.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR009011. Man6P_isomerase_rcpt-bd_dom.
    IPR028146. PRKCSH_N.
    [Graphical view]
    PANTHERiPTHR12630:SF1. PTHR12630:SF1. 1 hit.
    PfamiPF13202. EF-hand_5. 2 hits.
    PF12999. PRKCSH-like. 1 hit.
    [Graphical view]
    SMARTiSM00192. LDLa. 1 hit.
    [Graphical view]
    SUPFAMiSSF50911. SSF50911. 1 hit.
    PROSITEiPS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1WC34-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLLLLLLPL CWAVEVKRPR GVSLSNHHFY DESKPFTCLD GTATIPFDQV    50
    NDDYCDCKDG SDEPGTAACP NGSFHCTNTG YKPLYILSSR VNDGVCDCCD 100
    GTDEYNSGTV CENTCREKGR KEKESLQQLA EVTREGFRLK KILIEEWKTA 150
    REEKQSKLLE LQAGKKSLED QVETLRTAKE EAERPEKEAK DQHRKLWEEQ 200
    QAAAKARREQ ELAASAFQEL DDNMDGLVSL AELQTHPELD TDGDGGLSEE 250
    EAQALLSGDT QTDTTSFYDR VWAAIRDKYR SEVPPTDIPV PEVTEPKEEK 300
    LPVLPPMEEE EEEEEPEEEE EEEEEEVPGE QPKEVPPPQQ PLRPPSPAED 350
    EKMPPYDEET QAIIDAAQEA RNKFEEVERS LKEMEESIRS LEQEISFDFG 400
    PSGEFAYLYS QCYELTTNEY VYRLCPFKLV SQKPKHGGSP TSLGTWGSWA 450
    GPDDDKFSAM KYEQGTGCWQ GPNRSTTVRL LCGKETVVTS TTEPSRCEYL 500
    MELMTPAACP EPPPEVPTDG DHDEL 525
    Length:525
    Mass (Da):59,218
    Last modified:May 20, 2008 - v1
    Checksum:iC9C1089E36012BE8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06053688 Genomic DNA. No translation available.
    BC161987 mRNA. Translation: AAI61987.1.
    CH473993 Genomic DNA. Translation: EDL78243.1.
    RefSeqiNP_001100276.1. NM_001106806.2.
    XP_006242695.1. XM_006242633.1.
    UniGeneiRn.104417.

    Genome annotation databases

    EnsembliENSRNOT00000018009; ENSRNOP00000018009; ENSRNOG00000013360.
    GeneIDi300445.
    KEGGirno:300445.
    UCSCiRGD:1309628. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06053688 Genomic DNA. No translation available.
    BC161987 mRNA. Translation: AAI61987.1 .
    CH473993 Genomic DNA. Translation: EDL78243.1 .
    RefSeqi NP_001100276.1. NM_001106806.2.
    XP_006242695.1. XM_006242633.1.
    UniGenei Rn.104417.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000018009.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000018009 ; ENSRNOP00000018009 ; ENSRNOG00000013360 .
    GeneIDi 300445.
    KEGGi rno:300445.
    UCSCi RGD:1309628. rat.

    Organism-specific databases

    CTDi 5589.
    RGDi 1309628. Prkcsh.

    Phylogenomic databases

    eggNOGi NOG289998.
    GeneTreei ENSGT00510000047770.
    HOGENOMi HOG000007805.
    HOVERGENi HBG051738.
    KOi K08288.
    OMAi DHKEQID.
    OrthoDBi EOG7DZ8JX.
    TreeFami TF329550.

    Enzyme and pathway databases

    Reactomei REACT_196231. Advanced glycosylation endproduct receptor signaling.
    REACT_196411. N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
    REACT_196415. Calnexin/calreticulin cycle.

    Miscellaneous databases

    NextBioi 646903.
    PROi B1WC34.

    Gene expression databases

    Genevestigatori B1WC34.

    Family and domain databases

    Gene3Di 2.70.130.10. 2 hits.
    4.10.400.10. 1 hit.
    InterProi IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR026874. Glucosidase_2_bsu.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR009011. Man6P_isomerase_rcpt-bd_dom.
    IPR028146. PRKCSH_N.
    [Graphical view ]
    PANTHERi PTHR12630:SF1. PTHR12630:SF1. 1 hit.
    Pfami PF13202. EF-hand_5. 2 hits.
    PF12999. PRKCSH-like. 1 hit.
    [Graphical view ]
    SMARTi SM00192. LDLa. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50911. SSF50911. 1 hit.
    PROSITEi PS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LungImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    5. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiB1WC34_RAT
    AccessioniPrimary (citable) accession number: B1WC34
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3