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Protein

Mannosyltransferase

Gene

Alg12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-446193. Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein.

Protein family/group databases

CAZyiGT22. Glycosyltransferase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
MannosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:Alg12Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1304826. Alg12.

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 33HelicalUniRule annotationAdd BLAST22
Transmembranei69 – 86HelicalUniRule annotationAdd BLAST18
Transmembranei98 – 116HelicalUniRule annotationAdd BLAST19
Transmembranei122 – 141HelicalUniRule annotationAdd BLAST20
Transmembranei148 – 166HelicalUniRule annotationAdd BLAST19
Transmembranei172 – 198HelicalUniRule annotationAdd BLAST27
Transmembranei210 – 233HelicalUniRule annotationAdd BLAST24
Transmembranei261 – 282HelicalUniRule annotationAdd BLAST22
Transmembranei289 – 307HelicalUniRule annotationAdd BLAST19
Transmembranei313 – 333HelicalUniRule annotationAdd BLAST21
Transmembranei345 – 364HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000004591.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061731.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 22 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2516. Eukaryota.
ENOG410XR38. LUCA.
GeneTreeiENSGT00550000075005.
HOGENOMiHOG000265945.
HOVERGENiHBG050486.
KOiK03847.
OMAiNWRYDKR.
OrthoDBiEOG091G07LQ.

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1WBY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKKSSGRQ SLLPLGLLVT VAAIHLVACP YTKVEESFNL QATHDLLYHQ
60 70 80 90 100
LDIDKYDHHE FPGVVPRTFL GPLLIAAFSS PVVYVLSLLE VSRFYSQLIV
110 120 130 140 150
RGVLGLGVIF GLWTLQKAVR QQFGATVAVM FCWISATQFH LMFYCTRTLP
160 170 180 190 200
NVLALAVVLP ALTAWLQHRW AVFVWLSAFV IIGFRAELAM LLGIMLLLTL
210 220 230 240 250
YQRRMSVARL LQHAIPAGIL CLGLTVAVDS YFWRYLVWPE GVVLWYNTVL
260 270 280 290 300
NKSSNWGTSP LLWYFYSALP RGLGCSLLFI PLGAVDRRTF ALALPSLGFV
310 320 330 340 350
ALYSLLPHKE LRFIIYTFPV LNIMAARGCT YVLNKKSWPY KVRALLVFGH
360 370 380 390 400
VVVNVASTAT SLYVSHFNYP GGVAMQRLHE LVPPQTDVLV HIDVAAAQTG
410 420 430 440 450
VSRFLQVNDD WRYDKREDVQ LGAAGMLDYT HIIMEAVPGH LALYRDTHRV
460 470 480
LARIEATTGV SLNLMKVPPF DVSLQTKLVL LERLLRPA
Length:488
Mass (Da):54,709
Last modified:May 20, 2008 - v1
Checksum:iAC94D5E810E475A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058656 Genomic DNA. No translation available.
BC161934 mRNA. Translation: AAI61934.1.
RefSeqiNP_001101574.2. NM_001108104.2.
XP_017450363.1. XM_017594874.1.
XP_017450364.1. XM_017594875.1.
XP_017450365.1. XM_017594876.1.
XP_017450366.1. XM_017594877.1.
UniGeneiRn.30142.

Genome annotation databases

EnsembliENSRNOT00000065848; ENSRNOP00000061731; ENSRNOG00000004591.
GeneIDi315212.
KEGGirno:315212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058656 Genomic DNA. No translation available.
BC161934 mRNA. Translation: AAI61934.1.
RefSeqiNP_001101574.2. NM_001108104.2.
XP_017450363.1. XM_017594874.1.
XP_017450364.1. XM_017594875.1.
XP_017450365.1. XM_017594876.1.
XP_017450366.1. XM_017594877.1.
UniGeneiRn.30142.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061731.

Protein family/group databases

CAZyiGT22. Glycosyltransferase Family 22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000065848; ENSRNOP00000061731; ENSRNOG00000004591.
GeneIDi315212.
KEGGirno:315212.

Organism-specific databases

CTDi79087.
RGDi1304826. Alg12.

Phylogenomic databases

eggNOGiKOG2516. Eukaryota.
ENOG410XR38. LUCA.
GeneTreeiENSGT00550000075005.
HOGENOMiHOG000265945.
HOVERGENiHBG050486.
KOiK03847.
OMAiNWRYDKR.
OrthoDBiEOG091G07LQ.

Enzyme and pathway databases

ReactomeiR-RNO-446193. Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein.

Gene expression databases

BgeeiENSRNOG00000004591.

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1WBY3_RAT
AccessioniPrimary (citable) accession number: B1WBY3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: November 30, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.