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Protein

Mannosyltransferase

Gene

Alg12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Protein family/group databases

CAZyiGT22 Glycosyltransferase Family 22

Names & Taxonomyi

Protein namesi
Recommended name:
MannosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:Alg12Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1304826 Alg12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 33HelicalUniRule annotationAdd BLAST22
Transmembranei69 – 86HelicalUniRule annotationAdd BLAST18
Transmembranei98 – 116HelicalUniRule annotationAdd BLAST19
Transmembranei122 – 141HelicalUniRule annotationAdd BLAST20
Transmembranei148 – 166HelicalUniRule annotationAdd BLAST19
Transmembranei172 – 198HelicalUniRule annotationAdd BLAST27
Transmembranei210 – 233HelicalUniRule annotationAdd BLAST24
Transmembranei261 – 282HelicalUniRule annotationAdd BLAST22
Transmembranei289 – 307HelicalUniRule annotationAdd BLAST19
Transmembranei313 – 333HelicalUniRule annotationAdd BLAST21
Transmembranei345 – 364HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000004591

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061731

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 22 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2516 Eukaryota
ENOG410XR38 LUCA
GeneTreeiENSGT00550000075005
HOGENOMiHOG000265945
HOVERGENiHBG050486
KOiK03847
OMAiAIYSLQP
OrthoDBiEOG091G07LQ

Family and domain databases

InterProiView protein in InterPro
IPR005599 GPI_mannosylTrfase
PANTHERiPTHR22760 PTHR22760, 1 hit
PfamiView protein in Pfam
PF03901 Glyco_transf_22, 1 hit

Sequencei

Sequence statusi: Complete.

B1WBY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKKSSGRQ SLLPLGLLVT VAAIHLVACP YTKVEESFNL QATHDLLYHQ
60 70 80 90 100
LDIDKYDHHE FPGVVPRTFL GPLLIAAFSS PVVYVLSLLE VSRFYSQLIV
110 120 130 140 150
RGVLGLGVIF GLWTLQKAVR QQFGATVAVM FCWISATQFH LMFYCTRTLP
160 170 180 190 200
NVLALAVVLP ALTAWLQHRW AVFVWLSAFV IIGFRAELAM LLGIMLLLTL
210 220 230 240 250
YQRRMSVARL LQHAIPAGIL CLGLTVAVDS YFWRYLVWPE GVVLWYNTVL
260 270 280 290 300
NKSSNWGTSP LLWYFYSALP RGLGCSLLFI PLGAVDRRTF ALALPSLGFV
310 320 330 340 350
ALYSLLPHKE LRFIIYTFPV LNIMAARGCT YVLNKKSWPY KVRALLVFGH
360 370 380 390 400
VVVNVASTAT SLYVSHFNYP GGVAMQRLHE LVPPQTDVLV HIDVAAAQTG
410 420 430 440 450
VSRFLQVNDD WRYDKREDVQ LGAAGMLDYT HIIMEAVPGH LALYRDTHRV
460 470 480
LARIEATTGV SLNLMKVPPF DVSLQTKLVL LERLLRPA
Length:488
Mass (Da):54,709
Last modified:May 20, 2008 - v1
Checksum:iAC94D5E810E475A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058656 Genomic DNA No translation available.
BC161934 mRNA Translation: AAI61934.1
RefSeqiNP_001101574.2, NM_001108104.2
XP_017450363.1, XM_017594874.1
XP_017450364.1, XM_017594875.1
XP_017450365.1, XM_017594876.1
XP_017450366.1, XM_017594877.1
UniGeneiRn.30142

Genome annotation databases

EnsembliENSRNOT00000065848; ENSRNOP00000061731; ENSRNOG00000004591
GeneIDi315212
KEGGirno:315212

Similar proteinsi

Entry informationi

Entry nameiB1WBY3_RAT
AccessioniPrimary (citable) accession number: B1WBY3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: March 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health