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Protein

Armadillo repeat-containing protein 10

Gene

Armc10

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53 (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processGrowth regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Armadillo repeat-containing protein 10
Gene namesi
Name:Armc10
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1305915 Armc10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 29HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003467911 – 306Armadillo repeat-containing protein 10Add BLAST306

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei43PhosphoserineCombined sources1
Modified residuei48PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiB1WBW4
PeptideAtlasiB1WBW4
PRIDEiB1WBW4

PTM databases

iPTMnetiB1WBW4
PhosphoSitePlusiB1WBW4

Expressioni

Gene expression databases

BgeeiENSRNOG00000012785
GenevisibleiB1WBW4 RN

Interactioni

Subunit structurei

Interacts with the DNA-binding domain of p53/TP53.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000042700

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati101 – 143ARMAdd BLAST43

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IVCU Eukaryota
ENOG4112958 LUCA
GeneTreeiENSGT00550000074488
HOGENOMiHOG000231611
HOVERGENiHBG080349
InParanoidiB1WBW4
OMAiCLKIEGH
OrthoDBiEOG091G0PCU
PhylomeDBiB1WBW4
TreeFamiTF335652

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold
PfamiView protein in Pfam
PF04826 Arm_2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

B1WBW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGARDVGWV AAGLVLGAGA CYCIYRLTRG PRRGGRRLRP SRSAEDLTEG
60 70 80 90 100
SYDAILSAEQ LEKLLYLLES TDDPIITEKA LVTLGNNAAF STNQAIIREL
110 120 130 140 150
GGIPIVGSKI NSLNQSIKEK ALNALNNLSV NVENQTKIKI YVRQVCEDVF
160 170 180 190 200
ADPLNSAVQL AALRLLTNMT VTNDYQHLLS NYITGLLHLL LIGNGSTKVQ
210 220 230 240 250
VLKLLLNLSE NPAMTEGLLS AQVDSSFLSL YDGQMANEIL LRALTLFQNI
260 270 280 290 300
NNCLRVEGRL ANQLPFAKGS LFFLLYGEEC AQKMKALACH PDVDVKEKAL

AIKPKF
Length:306
Mass (Da):33,422
Last modified:May 20, 2008 - v1
Checksum:iC650BA2C13ECDED1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161913 mRNA Translation: AAI61913.1
RefSeqiNP_001100046.2, NM_001106576.2
UniGeneiRn.2408

Genome annotation databases

EnsembliENSRNOT00000044020; ENSRNOP00000042700; ENSRNOG00000012785
GeneIDi296758
KEGGirno:296758

Similar proteinsi

Entry informationi

Entry nameiARM10_RAT
AccessioniPrimary (citable) accession number: B1WBW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: May 20, 2008
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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