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Protein
Submitted name:

Angiotensin II receptor, type 2

Gene

Agtr2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Angiotensin II receptor, type 2Imported
Submitted name:
Angiotensin II receptor, type 2, isoform CRA_aImported
Gene namesi
Name:Agtr2Imported
ORF Names:rCG_53260Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2072. Agtr2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 70HelicalSequence analysisAdd BLAST22
Transmembranei82 – 100HelicalSequence analysisAdd BLAST19
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei160 – 181HelicalSequence analysisAdd BLAST22
Transmembranei217 – 234HelicalSequence analysisAdd BLAST18
Transmembranei254 – 278HelicalSequence analysisAdd BLAST25
Transmembranei298 – 321HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064709.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 318G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST258

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG104998.
KOiK04167.
OMAiNCSHKPS.
OrthoDBiEOG091G0HEN.

Family and domain databases

InterProiIPR000147. ATII_AT2_rcpt.
IPR000248. ATII_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00241. ANGIOTENSINR.
PR00636. ANGIOTENSN2R.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1WBL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDNFSFAAT SRNITSSLPF DNLNATGTNE SAFNCSHKPA DKHLEAIPVL
60 70 80 90 100
YYMIFVIGFA VNIVVVSLFC CQKGPKKVSS IYIFNLAVAD LLLLATLPLW
110 120 130 140 150
ATYYSYRYDW LFGPVMCKVF GSFLTLNMFA SIFFITCMSV DRYQSVIYPF
160 170 180 190 200
LSQRRNPWQA SYVVPLVWCM ACLSSLPTFY FRDVRTIEYL GVNACIMAFP
210 220 230 240 250
PEKYAQWSAG IALMKNILGF IIPLIFIATC YFGIRKHLLK TNSYGKNRIT
260 270 280 290 300
RDQVLKMAAA VVLAFIICWL PFHVLTFLDA LTWMGIINSC EVIAVIDLAL
310 320 330 340 350
PFAILLGFTN SCVNPFLYCF VGNRFQQKLR SVFRVPITWL QGKRETMSCR
360
KSSSLREMDT FVS
Length:363
Mass (Da):41,331
Last modified:May 20, 2008 - v1
Checksum:i4FE4551A41336650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161802 mRNA. Translation: AAI61802.1.
CH473991 Genomic DNA. Translation: EDM10788.1.
CH473991 Genomic DNA. Translation: EDM10789.1.
RefSeqiNP_036626.1. NM_012494.3.
XP_006257494.1. XM_006257432.3.
UniGeneiRn.162367.

Genome annotation databases

GeneIDi24182.
KEGGirno:24182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161802 mRNA. Translation: AAI61802.1.
CH473991 Genomic DNA. Translation: EDM10788.1.
CH473991 Genomic DNA. Translation: EDM10789.1.
RefSeqiNP_036626.1. NM_012494.3.
XP_006257494.1. XM_006257432.3.
UniGeneiRn.162367.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064709.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi24182.
KEGGirno:24182.

Organism-specific databases

CTDi186.
RGDi2072. Agtr2.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG104998.
KOiK04167.
OMAiNCSHKPS.
OrthoDBiEOG091G0HEN.

Family and domain databases

InterProiIPR000147. ATII_AT2_rcpt.
IPR000248. ATII_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00241. ANGIOTENSINR.
PR00636. ANGIOTENSN2R.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1WBL8_RAT
AccessioniPrimary (citable) accession number: B1WBL8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: November 30, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.