Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hexokinase

Gene

hk2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_301855. Glucose transport.
REACT_328358. Glycolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:hk2Imported
Synonyms:LOC100145699Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-5817381. hk2.

PTM / Processingi

Proteomic databases

PaxDbiB1WAR7.

Expressioni

Gene expression databases

BgeeiB1WAR7.
ExpressionAtlasiB1WAR7. baseline.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000060081.

Structurei

3D structure databases

ProteinModelPortaliB1WAR7.
SMRiB1WAR7. Positions 16-907.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
HOVERGENiHBG005020.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1WAR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNPRGDETH DNHQVKCNQI ECCLQPFHLS QVQLLSVRDL MLANMERGLM
60 70 80 90 100
KTPQKPSTLK MLPTYVRSTP DGTERGDFLV LDLGGAQFRI LHVELKDSAK
110 120 130 140 150
VEMESQVYAI PDEVMHGTGQ QLFDHVAECL GRFLRQQKLH QKVLPLGFTF
160 170 180 190 200
SFPCVQSQLD KSVLISWTKG FHCSDVEGKD VVHLLREAIC RQGDYEVDVI
210 220 230 240 250
AIVNDTVGAM MSCGYQDHSC EVGFIVGTGT NLCYMEEMGN VESVEGDEGK
260 270 280 290 300
MCINTEWGAL GDDGELSSIQ TEIDKQLDQN SLVSGKQCFD KLVSGMYMGE
310 320 330 340 350
IVRLILVKLA NQGLLFDGTT TQALLSKGCF ETKHVSAIED DHSGLSSARK
360 370 380 390 400
ILSVLGLNPS EQDCVNVQQV CSAVSTRSAN LCAAGLAAVA ARLQCNSQDP
410 420 430 440 450
NRKITIGVDG SVYKQHPKFS QRLHSALQHL APKCQINFLI SEDGSGKGTA
460 470 480 490 500
IVTAVAKRLA AQRHQIDEIL APFQLSQAKL EEVQSRMRTE MAIGLCKDTH
510 520 530 540 550
ASATVKMLPT YVRSTPDGTE RGDFIALDLG GTNFRVLYVH IGRREDVGVQ
560 570 580 590 600
IVSKTYSLPQ EIIQGTGVKL FDHIIDCISE FQSENNLRGR RLPLGFTFSF
610 620 630 640 650
PCKQTNLDQG ILMTWTKGFS ASGCVGKDVV MLLREAAVRK KNNDLIVVAL
660 670 680 690 700
VNDTVGTMMT CGYSDPACEI GLIVGTGTNA CYMEELRNVE LLDGDEGKMC
710 720 730 740 750
VNMEWGAFGD NNCLEDIATS FDRDVDKFSI NPGKQRYEKM ISGMYLGEIV
760 770 780 790 800
RQILIILTQR KILFGGNISE RLKTRDIFPT RFLSLIESDT LGLVQVRSIL
810 820 830 840 850
TDLGLRSTCD DTMLVKEVCT VVSRRAAQLC AAGIAAVVEK MRENRGLEQL
860 870 880 890 900
KVTVGVDGTL YKLHPHFAGV VHETVKVLAP RCDVTFLQSD DGSGKGAALI
910
TAVACRIAGA EARAA
Length:915
Mass (Da):100,349
Last modified:May 20, 2008 - v1
Checksum:i7AE4E512DA1D2E6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161474 mRNA. Translation: AAI61474.1.
RefSeqiNP_001120545.1. NM_001127073.1.
UniGeneiStr.18812.

Genome annotation databases

GeneIDi100145699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161474 mRNA. Translation: AAI61474.1.
RefSeqiNP_001120545.1. NM_001127073.1.
UniGeneiStr.18812.

3D structure databases

ProteinModelPortaliB1WAR7.
SMRiB1WAR7. Positions 16-907.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000060081.

Proteomic databases

PaxDbiB1WAR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100145699.

Organism-specific databases

CTDi3099.
XenbaseiXB-GENE-5817381. hk2.

Phylogenomic databases

eggNOGiCOG5026.
HOVERGENiHBG005020.

Enzyme and pathway databases

ReactomeiREACT_301855. Glucose transport.
REACT_328358. Glycolysis.

Gene expression databases

BgeeiB1WAR7.
ExpressionAtlasiB1WAR7. baseline.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole embryoImported.

Entry informationi

Entry nameiB1WAR7_XENTR
AccessioniPrimary (citable) accession number: B1WAR7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: June 24, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.